Treatment strategies for autoimmune encephalitis

YW Shin, ST Lee, KI Park, KH Jung… - Therapeutic …, 2018 - journals.sagepub.com
Autoimmune encephalitis is one of the most rapidly growing research topics in neurology.
Along with discoveries of novel antibodies associated with the disease, clinical experience …

Prognosticating autoimmune encephalitis: a systematic review

J Broadley, U Seneviratne, P Beech, K Buzzard… - Journal of …, 2019 - Elsevier
Objective To perform a systematic review of the current scientific literature in order to identify
variables associated with patient prognosis in autoimmune encephalitis. Methods We …

Seizures and risk of epilepsy in autoimmune and other inflammatory encephalitis

M Spatola, J Dalmau - Current opinion in neurology, 2017 - journals.lww.com
Although seizures are frequent in all types of autoimmune encephalitis, the risk for chronic
epilepsy is dependent on the antigen: lower if located on the cell-surface, and higher if …

[HTML][HTML] Autoimmune epilepsy

KS Husari, D Dubey - Neurotherapeutics, 2019 - Elsevier
The field of autoimmune epilepsy has evolved substantially in the last few decades with
discovery of several neural autoantibodies and improved mechanistic understanding of …

Efficacy and safety of rituximab in autoimmune encephalitis: a meta‐analysis

G Nepal, YK Shing, JK Yadav, JH Rehrig… - Acta Neurologica …, 2020 - Wiley Online Library
Background Autoimmune encephalitis (AE) is a rare but debilitating neurological disease
where the body develops antibodies against neuronal cell surface/synaptic proteins …

Targeting inflammatory mediators in epilepsy: a systematic review of its molecular basis and clinical applications

G Costagliola, G Depietri, A Michev, A Riva… - Frontiers in …, 2022 - frontiersin.org
Introduction Recent studies prompted the identification of neuroinflammation as a potential
target for the treatment of epilepsy, particularly drug-resistant epilepsy, and refractory status …

Clinical course and features of seizures associated with LGI1-antibody encephalitis

KM Smith, D Dubey, GB Liebo, EP Flanagan… - Neurology, 2021 - AAN Enterprises
Background and Objectives To determine risk factors associated with clinical relapses and
development of chronic epilepsy in patients with anti–leucine-rich glioma-inactivated 1 …

Immunity, ion channels and epilepsy

TS Chen, MC Lai, HYI Huang, SN Wu… - International journal of …, 2022 - mdpi.com
Epilepsy is a common chronic neurological disorder in modern society. One of the major
unmet challenges is that current antiseizure medications are basically not disease …

MicroRNA-129-5p inhibits the development of autoimmune encephalomyelitis-related epilepsy by targeting HMGB1 through the TLR4/NF-kB signaling pathway

AH Liu, YT Wu, YP Wang - Brain research bulletin, 2017 - Elsevier
The study aimed to explore the effects of microRNA-129-5p (miR-129-5p) on the
development of autoimmune encephalomyelitis (AE)-related epilepsy by targeting HMGB1 …

Seizures associated with antibodies against cell surface antigens are acute symptomatic and not indicative of epilepsy: insights from long-term data

A Rada, R Birnbacher, C Gobbi, M Kurthen… - Journal of …, 2021 - Springer
Background Clinicians have questioned whether any disorder involving seizures and neural
antibodies should be called “(auto) immune epilepsy.” The concept of “acute symptomatic …