Standardized MRD quantification in European ALL trials: proceedings of the Second International Symposium on MRD assessment in Kiel, Germany, 18–20 …
M Brüggemann, A Schrauder, T Raff, H Pfeifer… - Leukemia, 2010 - nature.com
Assessment of minimal residual disease (MRD) has acquired a prominent position in
European treatment protocols for patients with acute lymphoblastic leukemia (ALL), on the …
European treatment protocols for patients with acute lymphoblastic leukemia (ALL), on the …
Immunophenotyping of acute leukemia and lymphoproliferative disorders: a consensus proposal of the European LeukemiaNet Work Package 10
MC Béné, T Nebe, P Bettelheim, B Buldini, H Bumbea… - Leukemia, 2011 - nature.com
Abstract The European LeukemiaNet (ELN), workpackage 10 (WP10) was designed to deal
with diagnosis matters using morphology and immunophenotyping. This group aimed at …
with diagnosis matters using morphology and immunophenotyping. This group aimed at …
EuroFlow antibody panels for standardized n-dimensional flow cytometric immunophenotyping of normal, reactive and malignant leukocytes
JJM Van Dongen, L Lhermitte, S Böttcher, J Almeida… - Leukemia, 2012 - nature.com
Most consensus leukemia & lymphoma antibody panels consist of lists of markers based on
expert opinions, but they have not been validated. Here we present the validated EuroFlow …
expert opinions, but they have not been validated. Here we present the validated EuroFlow …
Risk of relapse of childhood acute lymphoblastic leukemia is predicted by flow cytometric measurement of residual disease on day 15 bone marrow
G Basso, M Veltroni, MG Valsecchi… - Journal of clinical …, 2009 - ascopubs.org
Purpose Speed of blast clearance is an indicator of outcome in childhood acute
lymphoblastic leukemia (ALL). Availability of measurement of minimal residual disease …
lymphoblastic leukemia (ALL). Availability of measurement of minimal residual disease …
AIEOP‐BFM consensus guidelines 2016 for flow cytometric immunophenotyping of pediatric acute lymphoblastic leukemia
MN Dworzak, B Buldini, G Gaipa… - Cytometry Part B …, 2018 - Wiley Online Library
Immunophenotyping by flow cytometry (FCM) is a worldwide mainstay in leukemia
diagnostics. For concordant multicentric application, however, a gap exists between …
diagnostics. For concordant multicentric application, however, a gap exists between …
CD99 at the crossroads of physiology and pathology
M Pasello, MC Manara, K Scotlandi - Journal of cell communication and …, 2018 - Springer
CD99 is a cell surface protein with unique features and only partly defined mechanisms of
action. This molecule is involved in crucial biological processes, including cell adhesion …
action. This molecule is involved in crucial biological processes, including cell adhesion …
Multiparametric flow cytometry for MRD monitoring in hematologic malignancies: clinical applications and new challenges
G Riva, V Nasillo, AM Ottomano, G Bergonzini… - Cancers, 2021 - mdpi.com
Simple Summary In hematologic cancers, Minimal Residual Disease (MRD) monitoring,
using either molecular (PCR) or immunophenotypic (MFC) diagnostics, allows the …
using either molecular (PCR) or immunophenotypic (MFC) diagnostics, allows the …
CAR T cells targeting CD99 as an approach to eradicate T-cell acute lymphoblastic leukemia without normal blood cells toxicity
J Shi, Z Zhang, H Cen, H Wu, S Zhang, J Liu… - Journal of Hematology & …, 2021 - Springer
CAR T cell therapy has shown dramatic clinical success in relapsed or refractory B-ALL and
other hematological malignancies. However, the loss of specific antigens, cell fratricide, T …
other hematological malignancies. However, the loss of specific antigens, cell fratricide, T …
CD99 inhibits neural differentiation of human Ewing sarcoma cells and thereby contributes to oncogenesis
A Rocchi, MC Manara, M Sciandra… - The Journal of …, 2010 - Am Soc Clin Investig
Ewing sarcoma (EWS) is an aggressive bone tumor of uncertain cellular origin. CD99 is a
membrane protein that is expressed in most cases of EWS, although its function in the …
membrane protein that is expressed in most cases of EWS, although its function in the …
Applications of flow cytometric immunophenotyping in the diagnosis and posttreatment monitoring of B and T lymphoblastic leukemia/lymphoma
JA DiGiuseppe, BL Wood - Cytometry Part B: Clinical …, 2019 - Wiley Online Library
In this review, we discuss applications of flow cytometric immunophenotyping (FCI) in the
diagnostic evaluation and posttreatment monitoring of B and T lymphoblastic …
diagnostic evaluation and posttreatment monitoring of B and T lymphoblastic …