Y Wang, X Deng, R Zhang, H Lyu, S Xiao, D Guo… - Biology, 2024 - mdpi.com
Simple Summary TRPV6 is a highly selective channel for calcium ions and plays an important role in maintaining calcium homeostasis. Some evidence suggests that it is …
Covalent inhibitors are viable therapeutics. However, off-target reactivity challenges the field. Chemists have attempted to solve this issue by varying the reactivity attributes of …
Freeze-drying, also known as lyophilization, significantly improves the storage, stability, shelf life, and clinical translation of biopharmaceuticals. On the downside, this process faces …
Z Wang, H Yan, JC Boysen, CR Secreto… - Blood cancer …, 2022 - nature.com
Constitutively activated B cell receptor (BCR) signaling is a primary biological feature of chronic lymphocytic leukemia (CLL). The biological events controlled by BCR signaling in …
NK Mohamed, MA El-Mokhtar… - Bulletin of …, 2024 - bpsa.journals.ekb.eg
In this review, an overview of exhausted T cells in acute and chronic leukemias including myelocytic and lymphoblastic leukemia was made to browse this important subset of cells …
Märklin et al haben gezeigt, dass der genetische Verlust von NFAT2, bekannt als wichtiger Transkriptionsfaktor in der Lymphozytenentwicklung, einen aggressiven Verlauf der CLL …