Physiological Benefits of Oxygen-Terminating Extracellular Electron Transfer

Y Tokunou, M Toyofuku, N Nomura - Mbio, 2022 - Am Soc Microbiol
Extracellular electron transfer (EET) is a process via which certain microorganisms, such as
bacteria, exchange electrons with extracellular materials by creating an electrical link across …

The major role of Listeria monocytogenes folic acid metabolism during infection is the generation of N-formylmethionine

Y Feng, SK Chang, DA Portnoy - Mbio, 2023 - Am Soc Microbiol
Folic acid and its derivatives (folates) play central roles in one-carbon metabolism,
necessary for the synthesis of purines, pyrimidines, and some amino acids. Antifolate drugs …

Lactiplantibacillus plantarum uses ecologically relevant, exogenous quinones for extracellular electron transfer

ET Stevens, W Van Beeck, B Blackburn… - Mbio, 2023 - Am Soc Microbiol
Extracellular electron transfer (EET) is a metabolic process that frequently uses quinones to
couple intracellular redox reactions with extracellular electron acceptors. The physiological …

The intersection between bacterial metabolism and innate immunity

IC Acosta, F Alonzo 3rd - Journal of Innate Immunity, 2023 - karger.com
Background: The innate immune system is the first line of defense against microbial
pathogens and is essential for maintaining good health. If pathogens breach innate barriers …

[HTML][HTML] Insight in lag phase of Listeria monocytogenes during enrichment through proteomic and transcriptomic responses

JW Bannenberg, S Boeren, MH Zwietering… - Food Research …, 2024 - Elsevier
The dynamics of the enrichment-based detection procedure of the foodborne pathogen
Listeria monocytogenes from food still remains poorly understood. This enrichment is crucial …

Distinct energy-coupling factor transporter subunits enable flavin acquisition and extracytosolic trafficking for extracellular electron transfer in Listeria monocytogenes

R Rivera-Lugo, S Huang, F Lee, R Méheust… - Mbio, 2023 - Am Soc Microbiol
ABSTRACT A variety of electron transfer mechanisms link bacterial cytosolic electron pools
with functionally diverse redox activities in the cell envelope and extracellular space. In …

Targeting NAD+ regeneration enhances antibiotic susceptibility of Streptococcus pneumoniae during invasive disease

H Im, ML Pearson, E Martinez, KH Cichos, X Song… - Plos …, 2023 - journals.plos.org
Anaerobic bacteria are responsible for half of all pulmonary infections. One such pathogen
is Streptococcus pneumoniae (Spn), a leading cause of community-acquired pneumonia …

Effect of Fermentation Scale on Microbiota Dynamics and Metabolic Functions for Indigo Reduction

N Farjana, H Furukawa, H Sumi, I Yumoto - International Journal of …, 2023 - mdpi.com
During indigo dyeing fermentation, indigo reduction for the solubilization of indigo particles
occurs through the action of microbiota under anaerobic alkaline conditions. The original …

Full-Length NAD+-I Riboswitches Bind a Single Cofactor but Cannot Discriminate against Adenosine Triphosphate

Y Srivastava, ME Blau, JL Jenkins, JE Wedekind - Biochemistry, 2023 - ACS Publications
Bacterial riboswitches are structured RNAs that bind small metabolites to control
downstream gene expression. Two riboswitch classes have been reported to sense …

Synthetic lethality of Mycobacterium tuberculosis NADH dehydrogenases is due to impaired NADH oxidation

Y Xu, S Ehrt, D Schnappinger, T Beites - Mbio, 2023 - Am Soc Microbiol
ABSTRACT Type 2 NADH dehydrogenase (Ndh-2) is an oxidative phosphorylation enzyme
discussed as a promising drug target in different pathogens, including Plasmodium …