[PDF][PDF] Handbook of life course health development

N Halfon, CB Forrest, RM Lerner, EM Faustman - 2018 - library.oapen.org
Handbook of life course health development Neal Halfon· Christopher B. Forrest Richard M.
Lerner· Elaine M. Faustman Editors Handbook of Life Course Health Development Page 2 …

Computational tools for prioritizing candidate genes: boosting disease gene discovery

Y Moreau, LC Tranchevent - Nature Reviews Genetics, 2012 - nature.com
At different stages of any research project, molecular biologists need to choose—often
somewhat arbitrarily, even after careful statistical data analysis—which genes or proteins to …

STRING v9. 1: protein-protein interaction networks, with increased coverage and integration

A Franceschini, D Szklarczyk, S Frankild… - Nucleic acids …, 2012 - academic.oup.com
Complete knowledge of all direct and indirect interactions between proteins in a given cell
would represent an important milestone towards a comprehensive description of cellular …

Inductive matrix completion for predicting gene–disease associations

N Natarajan, IS Dhillon - Bioinformatics, 2014 - academic.oup.com
Motivation: Most existing methods for predicting causal disease genes rely on specific type
of evidence, and are therefore limited in terms of applicability. More often than not, the type …

Candidate gene prioritization with Endeavour

LC Tranchevent, A Ardeshirdavani… - Nucleic acids …, 2016 - academic.oup.com
Genomic studies and high-throughput experiments often produce large lists of candidate
genes among which only a small fraction are truly relevant to the disease, phenotype or …

Probability-based collaborative filtering model for predicting gene–disease associations

X Zeng, N Ding, A Rodríguez-Patón, Q Zou - BMC medical genomics, 2017 - Springer
Background Accurately predicting pathogenic human genes has been challenging in recent
research. Considering extensive gene–disease data verified by biological experiments, we …

Discovering disease-disease associations by fusing systems-level molecular data

M Žitnik, V Janjić, C Larminie, B Zupan, N Pržulj - Scientific reports, 2013 - nature.com
The advent of genome-scale genetic and genomic studies allows new insight into disease
classification. Recently, a shift was made from linking diseases simply based on their shared …

A survey of gene prioritization tools for mendelian and complex human diseases

O Zolotareva, M Kleine - Journal of integrative bioinformatics, 2019 - degruyter.com
Modern high-throughput experiments provide us with numerous potential associations
between genes and diseases. Experimental validation of all the discovered associations, let …

Drug repositioning through network pharmacology

H Ye, J Wei, K Tang, R Feuers… - Current topics in …, 2016 - ingentaconnect.com
Low drug productivity has been a significant problem of the pharmaceutical industry for
several decades even though numerous novel technologies were introduced during this …

Disease gene prediction by integrating ppi networks, clinical rna-seq data and omim data

P Luo, LP Tian, J Ruan, FX Wu - IEEE/ACM transactions on …, 2017 - ieeexplore.ieee.org
Disease gene prediction is a challenging task that has a variety of applications such as early
diagnosis and drug development. The existing machine learning methods suffer from the …