Caveolae are a highly abundant but enigmatic feature of mammalian cells. They form
remarkably stable membrane domains at the plasma membrane but can also function as …

The cloning of a G protein-coupled extracellular Ca2+ (Cao 2+)-sensing receptor (CaR) has
elucidated the molecular basis for many of the previously recognized effects of Cao 2+ on …

The cell biology of caveolae is a rapidly growing area of biomedical research. Caveolae are
known primarily for their ability to transport molecules across endothelial cells, but modern …

The clearest function of membrane lipids is to form amphipathic bilayers that surround cells
and organelles and block leakage of hydrophilic compounds while housing membrane …

Janmey, Paul A. The Cytoskeleton and Cell Signaling: Component Localization and
Mechanical Coupling. Physiol. Rev. 78: 763–781, 1998.—The three-dimensional …

The classical action of androgen receptor (AR) is to regulate gene transcriptional processes
via AR nuclear translocation, response element binding and recruitment of, or crosstalk with …

The endothelial isoform of nitric oxide synthase (eNOS) modulates cardiac myocyte function
and is expressed in the particulate subcellular fraction. We have previously shown that …

Tight junctions (TJ) of polarized epithelial cells regulate barrier function at mucosal surfaces.
Structural proteins of TJs include hyperphosphorylated occludin (HO) and the peripheral …

Macrophages are essential innate immune cells and form our first line of immune defense.
Also known as professional phagocytes, macrophages interact and take up various …

(1), the axon and cell body of neurons (2), and the head Detergent-resistant membrane
domains (DRMs) can and tail of sperm (3), compositionally distinct plasma be isolated from …