Structure and physiological actions of ghrelin

C Delporte - Scientifica, 2013 - Wiley Online Library
Ghrelin is a gastric peptide hormone, discovered as being the endogenous ligand of growth
hormone secretagogue receptor. Ghrelin is a 28 amino acid peptide presenting a unique n …

The effects of ghrelin on inflammation and the immune system

D Baatar, K Patel, DD Taub - Molecular and cellular endocrinology, 2011 - Elsevier
A number of hormones and metabolic mediators signal the brain of changes in the body's
energy status and when an imbalance occurs; the brain coordinates the appropriate …

Therapeutic potential of targeting the ghrelin pathway

G Colldén, MH Tschöp, TD Müller - International Journal of Molecular …, 2017 - mdpi.com
Ghrelin was discovered in 1999 as the endogenous ligand of the growth-hormone
secretagogue receptor 1a (GHSR1a). Since then, ghrelin has been found to exert a plethora …

Gut microbiota and diet in patients with different glucose tolerance

L Egshatyan, D Kashtanova, A Popenko… - Endocrine …, 2016 - ec.bioscientifica.com
Elevated C-terminal fibroblast growth factor 23 (C-FGF23) concentrations have been
reported in Gambian children with and without putative Ca-deficiency rickets. The aims of …

Cisplatin-induced skeletal muscle dysfunction: mechanisms and counteracting therapeutic strategies

E Conte, E Bresciani, L Rizzi, O Cappellari… - International journal of …, 2020 - mdpi.com
Among the severe side effects induced by cisplatin chemotherapy, muscle wasting is the
most relevant one. This effect is a major cause for a clinical decline of cancer patients, since …

Expression, regulation and biological actions of growth hormone (GH) and ghrelin in the immune system

N Hattori - Growth Hormone & IGF Research, 2009 - Elsevier
Immune and neuroendocrine systems have bidirectional communications. Growth hormone
(GH) and an orexigenic hormone ghrelin are expressed in various immune cells such as T …

Ghrelin promotes thymopoiesis during aging

VD Dixit, H Yang, Y Sun, AT Weeraratna… - The Journal of …, 2007 - Am Soc Clin Investig
The decline in adaptive immunity, T lymphocyte output, and the contraction of the TCR
repertoire with age is largely attributable to thymic involution. The loss of thymic function with …

Evaluation of anti-inflammatory effect of Withania somnifera root on collagen-induced arthritis in rats

A Gupta, S Singh - Pharmaceutical biology, 2014 - Taylor & Francis
Abstract Context: Withania somnifera (Linn.) Dunal (Solanaceae) has long been used as an
herb in Ayurvedic and indigenous medicine and has received intense attention in recent …

Ghrelin treatment causes increased food intake and retention of lean body mass in a rat model of cancer cachexia

MD DeBoer, XX Zhu, P Levasseur, MM Meguid… - …, 2007 - academic.oup.com
Cancer cachexia is a debilitating syndrome of anorexia and loss of lean body mass that
accompanies many malignancies. Ghrelin is an orexigenic hormone with a short half-life that …

Ghrelin, the peripheral hunger hormone

SC Higgins, M Gueorguiev, M Korbonits - Annals of medicine, 2007 - Taylor & Francis
In the current review we summarize the available data concerning the gastric hormone
ghrelin and its receptor. Ghrelin stimulates short‐term food intake and long‐term body …