Since the first pioneering studies on small deuterated peptides dating more than 20 years
ago, 1H detection has evolved into the most efficient approach for investigation of …

Proton detection developed in the last 20 years as the method of choice to study
biomolecules in the solid state. In perdeuterated proteins, proton dipolar interactions are …

The NMR spectra of side-chain protons in proteins provide important information, not only
about their structure and dynamics, but also about the mechanisms that regulate interactions …

The highly infectious disease COVID-19 caused by the Betacoronavirus SARS-CoV-2 poses
a severe threat to humanity and demands the redirection of scientific efforts and criteria to …

Resolution in proton solid state magic angle sample spinning (MAS) NMR is limited by the
intrinsically imperfect nature of coherent averaging induced by either MAS or multiple pulse …

One key bottleneck of solid‐state NMR spectroscopy is that 1H NMR spectra of organic
solids are often very broad due to the presence of a strong network of dipolar couplings. We …

The modulation of oligomeric viral targets at sub-stoichiometric ratios of drug to target has
been advocated for its efficacy and potency, but there are only a limited number of …

SARS-CoV-2 carries a sizeable number of proteins that are accessory to replication but may
be essential for virus–host interactions and modulation of the host immune response. Here …

Membrane proteins are known to exert many essential biological functions by forming
complexes in cell membranes. An example refers to the β‐barrel assembly machinery …

The hepatitis delta virus (HDV) S-HDAg and L-HDAg antigens are the two isoforms of the
single protein encoded by the viral genome. Together with the double-stranded RNA …