Neuronal nicotinic acetylcholine (nACh) receptors in the brain are more commonly
associated with modulatory events than mediation of synaptic transmission. nACh receptors …

Nicotinic acetylcholine receptors (nAChRs) are integral membrane proteins and prototypic
members of the ligand‐gated ion‐channel superfamily, which has precursors in the …

Alzheimer's disease produces a devastating decline in mental function, with profound effects
on learning and memory. Early consequences of the disease include the specific loss of …

Neuronal nicotinic acetylcholine receptors (nAChRs) with putative α3β4-subunits have been
implicated in the mediation of signaling in various systems, including ganglionic …

Exogenous application of acetylcholine elicits inward currents in hippocampal interneurons
that are mediated via α-bungarotoxin-sensitive nicotinic acetylcholine receptors, but synaptic …

A growing body of evidence indicates that neuronal nicotinic acetylcholine receptors
(nAChRs), in addition to promoting fast cholinergic transmission, may modulate other …

Synaptic modulation and long-term synaptic changes are thought to be the cellular
correlates for learning and memory (;;). The hippocampus is a center for learning and …

Acute and chronic effects of nicotine on the immune system are usually opposite; acute
treatment stimulates while chronic nicotine suppresses immune and inflammatory …

Autism spectrum disorder (ASD) is a neurodevelopmental condition affecting around 1% of
the population. We previously discovered that infant siblings of children with ASD had …

Glia constitute 90% of cells in the human nervous system, but relatively little is known about
their functions. We have been focusing on the potential synaptic roles of glia in the CNS. We …