Membrane fission by dynamin: what we know and what we need to know

B Antonny, C Burd, P De Camilli, E Chen… - The EMBO …, 2016 - embopress.org
The large GTP ase dynamin is the first protein shown to catalyze membrane fission.
Dynamin and its related proteins are essential to many cell functions, from endocytosis to …

The constriction and scission machineries involved in mitochondrial fission

F Kraus, MT Ryan - Journal of cell science, 2017 - journals.biologists.com
ABSTRACT A key event in the evolution of eukaryotic cells was the engulfment of an aerobic
bacterium by a larger anaerobic archaebacterium, leading to a close relationship between …

Mass photometry enables label-free tracking and mass measurement of single proteins on lipid bilayers

EDB Foley, MS Kushwah, G Young, P Kukura - Nature Methods, 2021 - nature.com
The quantification of membrane-associated biomolecular interactions is crucial to our
understanding of various cellular processes. State-of-the-art single-molecule approaches …

[HTML][HTML] Relaxation of loaded ESCRT-III spiral springs drives membrane deformation

N Chiaruttini, L Redondo-Morata, A Colom, F Humbert… - Cell, 2015 - cell.com
ESCRT-III is required for lipid membrane remodeling in many cellular processes, from
abscission to viral budding and multi-vesicular body biogenesis. However, how ESCRT-III …

Dynamin-related protein 1 has membrane constricting and severing abilities sufficient for mitochondrial and peroxisomal fission

SC Kamerkar, F Kraus, AJ Sharpe, TJ Pucadyil… - Nature …, 2018 - nature.com
Abstract Dynamin-related protein 1 (Drp1) is essential for mitochondrial and peroxisomal
fission. Recent studies propose that Drp1 does not sever but rather constricts mitochondrial …

The 2018 biomembrane curvature and remodeling roadmap

P Bassereau, R Jin, T Baumgart… - Journal of physics D …, 2018 - iopscience.iop.org
The importance of curvature as a structural feature of biological membranes has been
recognized for many years and has fascinated scientists from a wide range of different …

Physical constraints and forces involved in phagocytosis

V Jaumouillé, CM Waterman - Frontiers in immunology, 2020 - frontiersin.org
Phagocytosis is a specialized process that enables cellular ingestion and clearance of
microbes, dead cells and tissue debris that are too large for other endocytic routes. As such …

Time-resolved cryo-EM using Spotiton

VP Dandey, WC Budell, H Wei, D Bobe, K Maruthi… - Nature …, 2020 - nature.com
We present an approach for preparing cryo-electron microscopy (cryo-EM) grids to study
short-lived molecular states. Using piezoelectric dispensing, two independent streams of …

Getting around the cell: physical transport in the intracellular world

SS Mogre, AI Brown, EF Koslover - Physical Biology, 2020 - iopscience.iop.org
Eukaryotic cells face the challenging task of transporting a variety of particles through the
complex intracellular milieu in order to deliver, distribute, and mix the many components that …

Insight into the role of clathrin‐mediated endocytosis inhibitors in SARS‐CoV‐2 infection

SS Alkafaas, AM Abdallah, S Ghosh… - Reviews in Medical …, 2023 - Wiley Online Library
Emergence of SARS‐CoV‐2 variants warrants sustainable efforts to upgrade both the
diagnostic and therapeutic protocols. Understanding the details of cellular and molecular …