Nonalcoholic fatty liver disease (NAFLD) is characterized by excessive fat accumulation in
the livers of patients without a history of alcohol abuse. It is classified as either simple …

Natural product derivatives are essential in searching for compounds with important
chemical, biological, and medical applications. Naphthoquinones are secondary …

Topoisomerases II are ubiquitous enzymes with significant genotoxic effects in many critical
DNA processes. Additionally, epidermal growth factor receptor (EGFR) plays pivotal role in …

In this study, some benzimidazole-oxadiazole derivatives were synthesised and tested for
their in vitro anticancer activities on five cancer cell lines, including HeLa, MCF7, A549 …

This study of the interaction system of binucleophilic 3-substituted 4-amino-4 H-1, 2, 4-
triazole-5-thiols and 3-phenyl-2-propynal made it possible to develop a new approach to …

Cancer encompasses a group of pathologies with common characteristics, high incidence,
and prevalence in all countries. Although there are treatments available for this disease …

Quinones and their derivatives play an important role in pharmaceutical, medicinal, and
environmental applications. The biological activities of quinone derivatives against various …

The vascular endothelial growth factor receptor 2 (VEGFR2) and c-mesenchymal epithelial
transition factor (c-Met) are members of receptor tyrosine kinases which have a crucial role …

Chronic hepatitis C virus (cHCV) is a leading cause for liver cirrhosis (LC) and
hepatocellular carcinoma (HCC) globally. So far, there is no optimal non-invasive biomarker …

In this study, four novel naphthoquinone-thiazole hybrids bearing adamantane were
synthesized by reaction of naphthoquinone-aroylthiourea derivatives with 1-adamantyl …