A variety of engineered materials have gained acceptance in orthopedic practice as
substitutes for autologous bone grafts, although the regenerative efficacy of these …

Bone defects are a common disease threatening the health of many people. Calcium
phosphate (CaP) is an ideal bone substitutive material that is widely used for bone repair …

Despite 40 years of efforts, researchers have failed to provide calcium phosphate bone graft
substitutes performing well enough to replace bone grafting procedures: their osteogenesis …

Coculture of osteoblasts and osteoclasts is a subject of interest in the understanding of how
magnesium (Mg)-based implants influence the bone metabolism and remodeling upon …

Osteoclasts are the cells responsible for physiological bone resorption. A specific
organization of their most prominent cytoskeletal structures, podosomes, is crucial for the …

Abstract Cobalt–chromium–molybdenum (CoCrMo) alloy, used for over five decades in
orthopedic implants, may corrode and release wear debris into the body during use. These …

The purpose of this study was to investigate the transformation of brushite (dicalcium
phosphate dihydrate, DCPD, CaHPO4· 2H2O) powders at 36.5° C in DMEM (Dulbecco's …

Osteoporosis is a worldwide disease with a very high prevalence in humans older than 50.
The main clinical consequences are bone fractures, which often lead to patient disability or …

An essential property of bone substitute materials is that they are integrated into the natural
bone remodelling process, which involves the resorption by osteoclast cells and the …

Magnesium-based implants have been shown to influence the surrounding bone structure.
In an attempt to partially reveal the cellular mechanisms involved in the remodelling of …