How to study anxiety and depression in rodent models of chronic pain?

M Kremer, LJ Becker, M Barrot… - European Journal of …, 2021 - Wiley Online Library
Mood disorders such as depression and anxiety are frequently observed in patients
suffering from chronic pain. Over time, different tests and models have been developed in …

Behavioral, biochemical and electrophysiological changes in spared nerve injury model of neuropathic pain

F Guida, D De Gregorio, E Palazzo, F Ricciardi… - International journal of …, 2020 - mdpi.com
Neuropathic pain is a pathological condition induced by a lesion or disease affecting the
somatosensory system, with symptoms like allodynia and hyperalgesia. It has a multifaceted …

Ion channels and receptors as determinants of microglial function

P Izquierdo, D Attwell, C Madry - Trends in Neurosciences, 2019 - cell.com
Microglia provide immune surveillance of the CNS. They display diverse behaviors,
including nondirectional and directed motility of their processes, phagocytosis of targets …

Chronic pain impact on rodents' behavioral repertoire

AM Cunha, J Pereira-Mendes, A Almeida… - Neuroscience & …, 2020 - Elsevier
Rodent models have been fundamental to understand chronic pain (CP) pathophysiology
and to test for potential treatments. Pain assessment in CP models is most frequently based …

[HTML][HTML] Fecal microbiota transplantation modulates gut microbiome composition and glial signaling in brain and colon of rats with neuropathic pain: evidence for …

CL Shen, H Deshmukh, JM Santos… - The Journal of frailty & …, 2024 - Elsevier
Despite evidence linking the gut microbiome to neuropathic pain (NP), it is not known if
altering gut microbiota can alleviate NP via the microbiome-gut-brain axis. This study …

Phonic Tics in a Rat Model of Tourette Syndrome Enable Research on Symptom-Based DBS

B Sagalajev, L Lennartz, N Mokhtari, M Szpak… - bioRxiv, 2023 - biorxiv.org
The lack of a rodent model for both motor and phonic tics hinders research on deep brain
stimulation (DBS) for refractory Tourette syndrome (TS). Striatal disinhibition with a GABA-A …

[PDF][PDF] Efeitos da dor neuropática na ansiedade em roedores: uma revisão sistemática

J Landeira-Fernandez - 2023 - maxwell.vrac.puc-rio.br
Resumo Saldanha, Alice da Luz; Landeira-Fernadez, Jesus. Efeitos da dor neuropática na
ansiedade em roedores: uma revisão sistemática. Rio de Janeiro, 2023, 71p. Dissertação …