The mammalian neuromuscular junction (NMJ) comprises a presynaptic terminal, a
postsynaptic receptor region on the muscle fiber (endplate), and the perisynaptic (terminal) …

Motor learning is accompanied by widespread changes within the motor cortex, but it is
unknown whether these changes are ultimately funneled through a stable corticospinal …

Human motor control requires the coordination of muscle activity under the anatomical
constraints imposed by the musculoskeletal system. Interactions within the central nervous …

The accuracy of neural circuit assembly relies on the precise spatial and temporal control of
synaptic specificity determinants during development. Hox transcription factors govern key …

After a stroke to the motor cortex, sprouting of spared contralateral corticospinal fibers into
the affected hemicord is one mechanism thought to mediate functional recovery. Little is …

Genetic mutations that cause amyotrophic lateral sclerosis (ALS), a progressively lethal
motor neuron disease, are commonly found in ubiquitously expressed genes. In addition to …

The establishment of spinal motor neuron subclass diversity is achieved through
developmental programs that are aligned with the organization of muscle targets in the limb …

Relay of muscle-derived sensory information to the CNS is essential for the execution of
motor behavior, but how proprioceptive sensory neurons (pSNs) establish functionally …

The motor system controls muscle movement through lower motor neurons in the spinal cord
and brainstem. Lower motor neurons are efferent neurons in the central nervous system …

Flight maneuvers require rapid sensory integration to generate adaptive motor output. Bats
achieve remarkable agility with modified forelimbs that serve as airfoils while retaining …