Oxidative stress reflects an imbalance between oxidants and antioxidants in favor of the
oxidants capable of evoking tissue damage. Like hydrogen sulfide (H2S) and nitric oxide …

Nuclear factor-erythroid 2 related factor 2 (Nrf2)-mediated signaling plays a central role in
maintaining cellular redox homeostasis of hepatic cells. Carbon monoxide releasing …

Bone metabolism occurs in the entire life of an individual and is required for maintaining
skeletal homeostasis. The imbalance between osteogenesis and osteoclastogenesis …

Dexmedetomidine (DEX) protects against liver damage caused by sepsis. The purpose of
this study was to confirm the regulatory effects of DEX on glycogen synthase kinase 3 beta …

Carbon monoxide (CO) is a known endogenous signaling molecule with potential
therapeutic indications in treating inflammation, cancer, neuroprotection, and sickle cell …

Atherogenesis involves multiple cell types undergoing robust metabolic processes resulting
in mitochondrial dysfunction, elevated reactive oxygen species (ROS), and consequent …

Acetaminophen (APAP) is widely used as an antifebrile and analgesic drug at
recommended doses, whereas an overdose of APAP can cause severe liver damage. The …

Cyclosporin A (CsA) is a common immunosuppressant, but its use is limited as it can cause
chronic kidney injury. Oxidative stress and apoptosis play a key role in CsA‐induced …

Carbon monoxide (CO) has long been known for its toxicity. However, in recent decades,
new applications for CO as a therapeutic compound have been proposed, and multiple …

Nonviral vectors are gaining importance as gene delivery systems. However, to meet the
large-scale applications, their sustainable production is of utmost importance. Hence, a cost …