Ganoderma lucidum, commonly known as “Lingzhi” in Chinese, are well-known medicinal
mushrooms. Lingzhi has been used in traditional Chinese herbal medicines for more than …

Brown algae (Phaeophyceae) have been consumed by humans for hundreds of years.
Current studies have shown that brown algae are rich sources of bioactive compounds with …

Triple helix conformation of polysaccharides is generally believed to be associated with their
biological activities. However, the formation mechanisms and analytical methods for the …

Fungi are increasingly being recognized as common members of the microbiomes found on
nearly all mucosal surfaces, and interest is growing in understanding how these organisms …

Orally administered drug entities have to survive the harsh gastrointestinal environment,
penetrate the enteric epithelia and circumvent hepatic metabolism before reaching the …

The progression of pancreatic oncogenesis requires immune-suppressive inflammation in
cooperation with oncogenic mutations. However, the drivers of intratumoral immune …

The innate immune system responds in a rapid and non‐specific manner against
immunologic threats; inflammation is part of this response. This is followed by a slower but …

β-Glucans are a group of biologically-active fibers or polysaccharides from natural sources
with proven medical significance. β-Glucans are known to have antitumor, anti-inflammatory …

The principle of trained immunity represents innate immune memory due to sustained,
mainly epigenetic, changes triggered by endogenous or exogenous stimuli in bone marrow …

Trained immunity is a de facto memory for innate immune responses, leading to long-term
functional reprogramming of innate immune cells. In physiological conditions, trained …