SOCS-JAK-STAT inhibitors and SOCS mimetics as treatment options for autoimmune uveitis, psoriasis, lupus, and autoimmune encephalitis

R Pandey, M Bakay, H Hakonarson - Frontiers in immunology, 2023 - frontiersin.org
Autoimmune diseases arise from atypical immune responses that attack self-tissue epitopes,
and their development is intricately connected to the disruption of the JAK-STAT signaling …

[HTML][HTML] Illuminating the pathogenic role of SARS-CoV-2: Insights into competing endogenous RNAs (ceRNAs) regulatory networks

MA Mir - Infection, Genetics and Evolution, 2024 - Elsevier
The appearance of SARS-CoV-2 in 2019 triggered a significant economic and health crisis
worldwide, with heterogeneous molecular mechanisms that contribute to its development …

The Potential Roles of Host Cell miRNAs in Fine-Tuning Bovine Coronavirus (BCoV) Molecular Pathogenesis, Tissue Tropism, and Immune Regulation

AU Shah, MG Hemida - Microorganisms, 2024 - mdpi.com
Bovine coronavirus (BCoV) infection causes significant economic loss to the dairy and beef
industries worldwide. BCoV exhibits dual tropism, infecting the respiratory and enteric tracts …

ORF3a of SARS-CoV-2 modulates PI3K/AKT signaling in human lung epithelial cells via hsa-miR-155-5p

F Ahmad, V Keshri, SK Singh - International Journal of Biological …, 2024 - Elsevier
SARS-CoV-2 infection results in cytokine burst, leading to proinflammatory responses in
lungs of COVID-19 patients. SARS-CoV-2 ORF3a triggers the generation of proinflammatory …

The Promotion of Humoral Immune Responses in Humans via SOCS1-Mediated Th2-Bias Following SARS-CoV-2 Vaccination

X Liu, J Han, R Cui, M Peng, H Song, R Li, G Chen - Vaccines, 2023 - mdpi.com
The effectiveness of SARS-CoV-2 vaccines varies among individuals. During the COVID-19
global pandemic, SARS-CoV-2 infection showed significant Th1 characteristics, suggesting …

Altered gene expression of miR-155 in peripheral blood mononuclear cells of Multiple Sclerosis patients: correlation with TH17 frequency, inflammatory cytokine …

S Alipour, P Amanallahi, B Baradaran… - Multiple Sclerosis and …, 2024 - Elsevier
In the chronic, organ-specific autoimmune disorder known as multiple sclerosis (MS), the
myelin sheath is attacked by immune cells, leading to damage to the central nervous system …

[PDF][PDF] A Comparative Evaluation of the Clinical Course, Laboratory Data and Chest CT scan Findings in Pediatric Patients with Covid-19 and Their Prognostic Value …

M Masjedi Esfahani, H Talari, J Azadbakht… - … Journal of Pediatrics, 2023 - researchgate.net
Background: Most research on children and adolescents with COVID-19, had limited sample
sizes and little clinical, laboratory, and radiological findings. The purpose of this research …

[PDF][PDF] The Effect of Mindful Parenting-Based Telepsychology on Behavioral Symptoms of ADHD Children during Covid-19 Outbreak

F Asarian, M Salehi, M Zalbagi Darestani… - … Journal of Pediatrics, 2024 - researchgate.net
Abstract Background: Attention Deficit/Hyperactivity Disorder (ADHD) is one of the most
common psychiatric disorders that cause major complications in children, and it is essential …

The Multifaceted and Paradoxical Roles of Toll-Like Receptors and Their Signaling Adaptors in Modulating Microglia Innate Immune Response to Neurotropic …

E Davis - 2024 - search.proquest.com
Despite recent advances in medicine, viral infections of the central nervous system (CNS)
constitute 20% of diagnosed neurological disorders. Left untreated, these infections can …