Spray drying is a well-established manufacturing technique which can be used to formulate
amorphous solid dispersions (ASDs) which is an effective strategy to deliver poorly water …

Application of amorphous solid dispersions (ASDs) is considered one of the most promising
approaches to increase the dissolution rate and extent of bioavailability of poorly water …

" Polymorphism in the Pharmaceutical Industry-Solid Form and Drug Development"
highlights the relevance of polymorphism in modern pharmaceutical chemistry, with a focus …

Introduction: Amorphous solid dispersions are considered as one of the most powerful
strategies to formulate poorly soluble drugs. They are made up of an active pharmaceutical …

When developing an amorphous solid dispersion (ASD), a prudent choice of polymer is
critical to several aspects of ASD performance including: processability, solid state stability …

Amorphous solid dispersion (ASD) is one of the formulation strategies for drugs displaying
low solubility and low oral bioavailability. In this study, high drug-loaded ASDs of drugs with …

Kinetically stabilized amorphous solid dispersions are inherently metastable systems.
Therefore, such systems are generally considered prone to recrystallization. In some cases …

Predensification and compression are unit operations imperative to the manufacture of
tablets and capsules. Such stress-inducing steps can cause destabilization of solid …

Inhibition of recrystallization of the drug substance in kinetically stabilized amorphous solid
dispersions (ASDs) within and beyond shelf life is still a matter of debate. Generally, these …

To date, the use of high explosives (HEs) has been largely limited to their crystalline forms.
The glassy forms of these materials have not received much attention. While the highest …