Coumarin-based derivatives with potential anti-HIV activity
Z Xu, Q Chen, Y Zhang, C Liang - Fitoterapia, 2021 - Elsevier
Acquired immunodeficiency syndrome (AIDS), as a result of human immunodeficiency virus
(HIV) infection which leads to severe suppression of immune functions, is an enormous …
(HIV) infection which leads to severe suppression of immune functions, is an enormous …
Structural, spectral, molecular docking, and molecular dynamics simulations of phenylthiophene-2-carboxylate compounds as potential anticancer agents
P Vennila, JS Al-Otaibi, G Venkatesh… - Polycyclic Aromatic …, 2024 - Taylor & Francis
Important biological compounds, namely, methyl 3-amino-4-(4-bromophenyl) thiophene-2-
carboxylate (BPTC) and methyl 3-amino-4-(4-chlorophenyl) thiophene-2-carboxylate …
carboxylate (BPTC) and methyl 3-amino-4-(4-chlorophenyl) thiophene-2-carboxylate …
[HTML][HTML] HIV-1 Reverse Transcriptase/Integrase dual inhibitors: A review of recent advances and structure-activity relationship studies
M Mahboubi-Rabbani, M Abbasi… - Iranian Journal of …, 2021 - ncbi.nlm.nih.gov
The significant threat to humanity is HIV infection, and it is uncertain whether a definitive
treatment or a safe HIV vaccine is. HIV-1 is continually evolving and resistant to commonly …
treatment or a safe HIV vaccine is. HIV-1 is continually evolving and resistant to commonly …
[HTML][HTML] Selective in-vitro enzymes' inhibitory activities of fingerprints compounds of Salvia species and molecular docking simulations
Abstract Recently Nutrition and Food Chemistry researches have been focused on plants
and their products or their secondary metabolites having anti-alzheimer, anti-cancer, anti …
and their products or their secondary metabolites having anti-alzheimer, anti-cancer, anti …
Design, synthesis, molecular modeling and anti-HIV assay of novel quinazolinone incorporated coumarin derivatives
M Safakish, Z Hajimahdi, MR Aghasadeghi… - Current HIV …, 2020 - ingentaconnect.com
Background: The emergence of drug-resistant viral strains has created the need for the
development of novel anti-HIV agents with a diverse structure that targets key enzymes in …
development of novel anti-HIV agents with a diverse structure that targets key enzymes in …
Versatile in silico modeling of partition coefficients of organic compounds in polydimethylsiloxane using linear and nonlinear methods
T Zhu, W Chen, RP Singh, Y Cui - Journal of Hazardous Materials, 2020 - Elsevier
Environmental fate, behavior and effects of hazardous organic compounds have recently
received great attention in diverse environmental phases, including water, atmosphere, soil …
received great attention in diverse environmental phases, including water, atmosphere, soil …
Experimental synthesis, biological evaluation, theoretical investigations of some novel benzoxazolinone based Schiff under eco-environmental conditions as potential …
In this paper, we have developed a new, non-hazardous and eco-friendly access route for
the synthesis of a novel Schiff bases containing 2-oxo-3H-benzoxazole scaffold 4 (af) by …
the synthesis of a novel Schiff bases containing 2-oxo-3H-benzoxazole scaffold 4 (af) by …
Design, synthesis, docking studies and biological activities novel 2, 3-diaryl-4-quinazolinone derivatives as anti-HIV-1 agents
Z Hajimahdi, R Zabihollahi… - Current HIV …, 2019 - ingentaconnect.com
Background: Although major efforts have been devoted to the effective treatment of HIV-1
infection, it has remained one of the leading causes of deaths around the world. So …
infection, it has remained one of the leading causes of deaths around the world. So …
Role of computational modelling in drug discovery for HIV
With over 36 million people currently living with HIV, HIV/AIDS continues to have devastating
effects on human health worldwide. Viral resistance to anti-HIV drugs remains a major cause …
effects on human health worldwide. Viral resistance to anti-HIV drugs remains a major cause …
QSAR Study on Diacylgycerol Acyltransferase-1 (DGAT-1) Inhibitor as Anti-diabetic using PSO-SVM Methods
IKAPP Pramana, RR Septiawan… - Jurnal RESTI (Rekayasa …, 2022 - jurnal.iaii.or.id
Diabetes mellitus is a chronic disease that can occur in anyone. Up until now, there are no
specific drugs have been found which can completely cure diabetes. One of the possible …
specific drugs have been found which can completely cure diabetes. One of the possible …