High levels of cholesterol are generally considered to be associated with atherosclerosis. In
the past two decades, however, a number of studies have shown that excess cholesterol …

Cholesterol homeostasis is essential in normal physiology of all cells. One of several
proteins involved in cholesterol homeostasis is the ATP-binding cassette transporter A1 …

Background Although the insulin-producing pancreatic β-cells are quite capable of adapting
to both acute and chronic changes in metabolic demand, persistently high demand for …

Insulin is produced by pancreatic β-cells, and once released to the blood, the hormone
stimulates glucose uptake and suppresses glucose production. Defects in both the …

Abstract Treatment with statins has transformed primary and secondary prevention of
cardiovascular disease (CVD), including thrombotic stroke. Evidence-based data …

Recent studies have shown that severe acute respiratory syndrome coronavirus 2 (SARS-
CoV-2) infection may induce metabolic distress, leading to hyperglycemia in patients …

Cholesterol plays an essential role in determining cell membrane physico-chemical
characteristics and functions. A proper membrane structure is critical in pancreatic β-cells for …

Cholesterol homeostasis is a highly regulated process in human body because of its several
functions underlying the biology of cell membranes, the synthesis of all steroid hormones …

Studying rats fed high cholesterol diet and a pancreatic β-cell line (Min6), we aimed to
determine the mechanisms by which quercetin protects against cholesterol-induced …

Chromogenic immunohistochemistry (immunostaining using an enzyme-labeled probe) is
an essential histochemical technique for analyzing pathogenesis and making a …