A rapidly growing body of literature indicates that adult neurogenesis in the hippocampus is
sensitive to a variety of environmental factors. The effects of emotionally salient experiences …

Insulin-like growth factor-binding protein-2 (IGFBP-2) is a pleiotropic polypeptide that
functions as autocrine and/or paracrine growth factors. IGFBP-2 is the most abundant of the …

Several lines of evidence suggest that the dysregulation of the immune system is an
important factor in the development of depression. Microglia are the resident macrophages …

Background Alzheimer's disease (AD) is the most common neurodegenerative disorder in
the elderly, resulting in gradual destruction of cognitive abilities. Research on the …

Cognitive and mental health are major determinants of quality of life, allowing integration
into society at all ages. Human epidemiological and animal studies indicate that in addition …

Currently, much attention is focused on the influence of mitochondrial disturbances at the
onset of depression. The goal of this study was to investigate the impact of prenatal stress …

Background: Posttraumatic stress disorder is an anxiety disorder characterized by deficits in
the extinction of aversive memories. Insulin-like growth factor 1 (IGF1) is the only growth …

A growing body of evidence has focused on the impact of mitochondrial disturbances in the
development of depression, but little data exist regarding the effects of chronic …

The effects of prenatal stress procedure were investigated in 3 months old male rats.
Prenatally stressed rats showed depressive-like behavior in the forced swim test, including …

Adult hippocampal neurogenesis (AHN) is involved in learning, memory, and stress, and
plays a significant role in neurodegenerative and psychiatric disorders. As an age …