[HTML][HTML] Silica nanoparticles: Biomedical applications and toxicity

Y Huang, P Li, R Zhao, L Zhao, J Liu, S Peng… - Biomedicine & …, 2022 - Elsevier
Silica nanoparticles (SiNPs) are composed of silicon dioxide, the most abundant compound
on Earth, and are used widely in many applications including the food industry, synthetic …

Prospects and hazards of silica nanoparticles: Biological impacts and implicated mechanisms

R Ding, Y Li, Y Yu, Z Sun, J Duan - Biotechnology Advances, 2023 - Elsevier
With the thrive of nanotechnology, silica nanoparticles (SiNPs) have been extensively
adopted in the agriculture, food, cosmetic, and even biomedical industries. Due to the mass …

Surface modification of nanoparticles to improve oil recovery Mechanisms: A critical review of the methods, influencing Parameters, advances and prospects

EN Ngouangna, MZ Jaafar, MNAM Norddin… - Journal of Molecular …, 2022 - Elsevier
The utilization of nanoparticles (NPs) in enhanced oil recovery (EOR) has a lot of benefits
however, the usage of bare NPs still has a few drawbacks, including instability …

Pulmonary toxicity of silica linked to its micro-or nanometric particle size and crystal structure: A review

V Marques Da Silva, M Benjdir, P Montagne, JC Pairon… - Nanomaterials, 2022 - mdpi.com
Silicon dioxide (SiO2) is a mineral compound present in the Earth's crust in two mineral
forms: crystalline and amorphous. Based on epidemiological and/or biological evidence, the …

Long-term respiratory exposure to amorphous silica nanoparticles promoted systemic inflammation and progression of fibrosis in a susceptible mouse model

X Li, Y Li, S Lv, H Xu, R Ma, Z Sun, Y Li, C Guo - Chemosphere, 2022 - Elsevier
Exposure to amorphous silica nanoparticles (SiNPs) has increased dramatically, and
concerns are growing about their potential health effects. However, their long-term systemic …

Silica nanoparticles induce cardiac injury and dysfunction via ROS/Ca2+/CaMKII signaling

Y Qi, H Xu, X Li, X Zhao, Y Li, X Zhou, S Chen… - Science of The Total …, 2022 - Elsevier
Interest is growing to better comprehend the interaction of silica nanoparticles (SiNPs) with
the cardiovascular system. In particular, the extremely small size, relatively large surface …

Exploiting Mass Spectrometry to Unlock the Mechanism of Nanoparticle-Induced Inflammasome Activation

G Gupta, J Kaur, K Bhattacharya, BJ Chambers… - ACS …, 2023 - ACS Publications
Nanoparticles (NPs) elicit sterile inflammation, but the underlying signaling pathways are
poorly understood. Here, we report that human monocytes are particularly vulnerable to …

Stimuli-responsive biodegradable silica nanoparticles: From native structure designs to biological applications

Q Qi, Q Shen, J Geng, W An, Q Wu, N Wang… - Advances in Colloid and …, 2024 - Elsevier
Due to their inherent advantages, silica nanoparticles (SiNPs) have greatly potential
applications as bioactive materials in biosensors/biomedicine. However, the long-term and …

Crystalline silica-induced endoplasmic reticulum stress promotes the pathogenesis of silicosis by augmenting proinflammatory interstitial pulmonary macrophages

H Yuan, Y He, Y Zhang, H Min, J Chen, C Li - Science of The Total …, 2024 - Elsevier
Crystalline silica (CS) particles are ubiquitously present in the environment, particularly in
occupational settings, and exposure to respirable CS causes silicosis, imposing a significant …

Amorphous silica nanoparticles caused lung injury through the induction of epithelial apoptosis via ROS/Ca2+/DRP1-mediated mitochondrial fission signaling

Y Li, Y Zhu, B Zhao, Q Yao, H Xu, S Lv, J Wang… - …, 2022 - Taylor & Francis
The adverse effects of amorphous silica nanoparticles (SiNPs) exposure on the respiratory
system were increasingly recognized, however, its potential pathogenesis still remains not …