Review of polysaccharide particle-based functional drug delivery

TG Barclay, CM Day, N Petrovsky, S Garg - Carbohydrate polymers, 2019 - Elsevier
This review investigates the significant role polysaccharide particles play in functional drug
delivery. The importance of these systems is due to the wide variety of polysaccharides and …

Therapeutic targets, novel drugs, and delivery systems for diabetes associated NAFLD and liver fibrosis

V Kumar, X Xin, J Ma, C Tan, N Osna… - Advanced drug delivery …, 2021 - Elsevier
Type 2 diabetes mellitus (T2DM) associated non-alcoholic fatty liver disease (NAFLD) is the
fourth-leading cause of death. Hyperglycemia induces various complications, including …

[HTML][HTML] Polysaccharide-based nanomedicines for cancer immunotherapy: A review

Y Zeng, Y Xiang, R Sheng, H Tomás, J Rodrigues… - Bioactive Materials, 2021 - Elsevier
Cancer immunotherapy is an effective antitumor approach through activating immune
systems to eradicate tumors by immunotherapeutics. However, direct administration of …

Pullulan: A novel molecule for biomedical applications

RS Singh, N Kaur, V Rana, JF Kennedy - Carbohydrate polymers, 2017 - Elsevier
Pullulan is an imperative natural polymer produced commercially by yeast like fungus
Aureobasidium pullulans. It is non-toxic, non-immunogenic, non-carcinogenic and non …

Therapeutic targeting of non-coding RNAs in cancer

O Slaby, R Laga, O Sedlacek - Biochemical journal, 2017 - portlandpress.com
The majority of the human genome encodes RNAs that do not code for proteins. These non-
coding RNAs (ncRNAs) affect normal expression of the genes, including oncogenes and …

Polyethylenimine: A versatile, multifunctional non-viral vector for nucleic acid delivery

AP Pandey, KK Sawant - Materials Science and Engineering: C, 2016 - Elsevier
Polyethylenimine (PEI) has recently been widely studied for the design of nucleic acid
delivery vehicles. Gene delivery using PEI involves condensation of DNA into compact …

Pullulan in biomedical research and development-A review

RS Singh, N Kaur, M Hassan, JF Kennedy - International journal of …, 2021 - Elsevier
Pullulan is an imperative microbial exo-polymer commercially produced by yeast like fungus
Aureobasidium pullulans. Its structure contains maltosyl repeating units which comprises …

Pullulan and pullulan derivatives as promising biomolecules for drug and gene targeting

RS Singh, N Kaur, JF Kennedy - Carbohydrate Polymers, 2015 - Elsevier
Pullulan is a water soluble exo-polysaccharide produced by yeast like fungus
Aureobasidium pullulans. Pullulan structure have a unique characteristic ie co-existence of …

Fungal exopolysaccharides: Properties, sources, modifications, and biomedical applications

M Hamidi, OV Okoro, PB Milan, MR Khalili… - Carbohydrate …, 2022 - Elsevier
Fungal exopolysaccharides (EPSs) are natural biopolymers with diverse potential
applications in the biomedical, packaging, cosmetic, and food industries. Fungal EPSs are …

[HTML][HTML] Biodegradable polymers for gene delivery

TJ Thomas, HA Tajmir-Riahi, CKS Pillai - Molecules, 2019 - mdpi.com
The cellular transport process of DNA is hampered by cell membrane barriers, and hence, a
delivery vehicle is essential for realizing the potential benefits of gene therapy to combat a …