Marine cone snails are carnivorous gastropods that use peptide toxins called conopeptides
both as a defense mechanism and as a means to immobilize and kill their prey. These …

Nicotinic acetylcholine receptors (nAChRs) are found throughout the mammalian body and
have been studied extensively because of their implication in a myriad of diseases. α …

Venom peptide toxins such as conotoxins play a critical role in the characterization of
nicotinic acetylcholine receptor (nAChR) structure and function and have potential as …

Peptides, defined as sequences of amino acids up to approximately 50 residues in length,
represent an extremely large reservoir of potentially bioactive compounds, referred to here …

Computational systems and methods are often being used in biological research, including
the understanding of cancer and the development of treatments. Simulations of tumor growth …

A pheochromocytoma of the rat adrenal medulla derived (aka PC12) cell-based assay for
dopamine measurement by luminescence detection was customized for the qualitative …

Background Conventional de novo drug design is costly and time consuming, making it
accessible to only the best resourced research organizations. An emergent approach to new …

KTM is a 16 amino acid peptide with the sequence WCCSYPGCYWSSSKWC. Here, we
present the nuclear magnetic resonance (NMR) structure and bioactivity of this rationally …

β2-nAChR促进小鼠海马CA1和CA3锥体神经元GABAA受体的功能成熟- PMC Back to Top
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Fungal infections caused by Candida albicans pose a serious threat to public health. The
rising drug resistance towards azoles, the current first-line antifungal treatment, warrants …