Abstract Treatment outcomes for major depressive disorder (MDD) need to be improved.
Presently, no clinically relevant tools have been established for stratifying subgroups or …

One in three adults with major depressive disorder (MDD) do not experience clinically
significant improvement after multiple sequential courses of antidepressants and have …

Major depressive disorder (MDD) is a chronic condition that affects one in six adults in the
US during their lifetime. The current practice of antidepressant medication prescription is a …

Specific challenges that profoundly affect the outcome of treatment for depression include 1)
patient engagement and retention in care and optimization of treatment adherence, 2) …

Selective serotonin reuptake inhibitors (SSRIs) are the most commonly prescribed class of
antidepressant (1) and are recommended as one of the first-line treatments (2–4) for major …

ObjectiveAtWoRC (Assessment in Work productivity and the Relationship with Cognitive
symptoms) was an interventional, open-label, Canadian study (NCT02332954) designed to …

Objectives Common mental health problems (CMHP) represent a major health issue and
burden to employees and employers. Under certain conditions work contributes to wellbeing …

Prospective predictors of suicide attempts were assessed in 118 subjects with borderline
personality disorder (BPD) after 10 or more years of follow-up. Mean (SD) time to follow-up …

ObjectiveThe Assessment in Work Productivity and the Relationship with Cognitive
Symptoms (AtWoRC) study aimed to assess the association between cognitive symptoms …

Background Currently, there are no valid clinical or biological markers to personalize the
treatment of depression. Recent evidence suggests that body mass index (BMI) may guide …