Current understanding of fear learning and memory in humans and animal models and the value of a linguistic approach for analyzing fear learning and memory in …

J Raber, S Arzy, JB Bertolus, B Depue, HE Haas… - Neuroscience & …, 2019 - Elsevier
Fear is an emotion that serves as a driving factor in how organisms move through the world.
In this review, we discuss the current understandings of the subjective experience of fear …

Innovative biomarkers in psychiatric disorders: a major clinical challenge in psychiatry

M Lozupone, D Seripa, E Stella… - Expert review of …, 2017 - Taylor & Francis
Introduction: Currently, the diagnosis of psychiatric illnesses is based upon DSM-5 criteria.
Although endophenotype-specificity for a particular disorder is discussed, the identification …

A pilot proteomic analysis of salivary biomarkers in autism spectrum disorder

AG Ngounou Wetie, KL Wormwood, S Russell… - Autism …, 2015 - Wiley Online Library
Autism spectrum disorder (ASD) prevalence is increasing, with current estimates at 1/68–
1/50 individuals diagnosed with an ASD. Diagnosis is based on behavioral assessments …

The role of biomarkers in psychiatry

M Lozupone, M La Montagna, F D'Urso… - Reviews on biomarker …, 2019 - Springer
Psychiatric illnesses are cognitive and behavioral disorders of the brain. At present,
psychiatric diagnosis is based on DSM-5 criteria. Even if endophenotype specificity for …

Animal models of PTSD: the socially isolated mouse and the biomarker role of allopregnanolone

G Pinna - Frontiers in behavioral neuroscience, 2019 - frontiersin.org
Post-traumatic stress disorder (PTSD) is a debilitating undertreated condition that affects 8%–
13% of the general population and 20%–30% of military personnel. Currently, there are no …

Identification of posttranslational modifications (PTMs) of proteins by mass spectrometry

R Aslebagh, KL Wormwood… - Advancements of mass …, 2019 - Springer
There are only 30,000 human genes, which, according to the central dogma from biology, it
means that there should be 30,000 mRNA and 30,000 proteins. However, there are at least …

Mitochondrial dysfunction and changes in high-energy compounds in different cellular models associated to hypoxia: implication to schizophrenia

LFS e Silva, MD Brito, JMC Yuzawa, TR Rosenstock - Scientific Reports, 2019 - nature.com
Schizophrenia (SZ) is a multifactorial mental disorder, which has been associated with a
number of environmental factors, such as hypoxia. Considering that numerous neural …

Proteomic approaches to identify blood-based biomarkers for depression and bipolar disorders

RL Preece, SYS Han, S Bahn - Expert Review of Proteomics, 2018 - Taylor & Francis
Introduction: Major depressive disorder (MDD) and bipolar disorder (BD) are leading causes
of disability worldwide, yet many people remain undiagnosed, are misdiagnosed, and/or …

A pilot proteomic study of protein markers in autism spectrum disorder

AG Ngounou Wetie, K Wormwood, J Thome… - …, 2014 - Wiley Online Library
Autism spectrum disorder (ASD) diagnosis is increasing, with 1/88 children believed to be
affected by the disorder, with a most recent survey suggesting numbers as high as 1/50 …

Biomarkers for PTSD at the interface of the endocannabinoid and neurosteroid axis

G Pinna - Frontiers in neuroscience, 2018 - frontiersin.org
In the search for reliable and, possibly, specific biomarkers for neuropsychiatric disorders,
growing evidence has demonstrated that biosynthesis of neuroactive steroids and the …