Non-invasive biomarkers for early detection of breast cancer
Simple Summary Early diagnosis of breast cancer greatly increases the chance of cure and
survival from the disease. The mammogram is widely used for early detection of breast …
survival from the disease. The mammogram is widely used for early detection of breast …
ER and PR signaling nodes during mammary gland development
The ovarian hormones estrogen and progesterone orchestrate postnatal mammary gland
development and are implicated in breast cancer. Most of our understanding of the …
development and are implicated in breast cancer. Most of our understanding of the …
The oral selective oestrogen receptor degrader (SERD) AZD9496 is comparable to fulvestrant in antagonising ER and circumventing endocrine resistance
A Nardone, H Weir, O Delpuech, H Brown… - British journal of …, 2019 - nature.com
Background The oestrogen receptor (ER) is an important therapeutic target in ER-positive
(ER+) breast cancer. The selective ER degrader (SERD), fulvestrant, is effective in patients …
(ER+) breast cancer. The selective ER degrader (SERD), fulvestrant, is effective in patients …
TFF3 and TFF1 expression levels are elevated in colorectal cancer and promote the malignant behavior of colon cancer by activating the EMT process
A Yusufu, P Shayimu, R Tuerdi… - International …, 2019 - spandidos-publications.com
Reports on the roles of the secreted trefoil factor (TFF) 1 and 3 in colorectal cancer (CRC)
and their underlying mechanisms of action in tumorigenesis are not common and are …
and their underlying mechanisms of action in tumorigenesis are not common and are …
[HTML][HTML] DEHP mediates drug resistance by directly targeting AhR in human breast cancer
TH Hsieh, CY Hsu, PJ Yang, CC Chiu, SS Liang… - Biomedicine & …, 2022 - Elsevier
Resistance to chemotherapy and hormonal therapy is a major clinical problem in breast
cancer medicine, especially for cancer metastasis and recurrence. Di (2-ethylhexyl) …
cancer medicine, especially for cancer metastasis and recurrence. Di (2-ethylhexyl) …
Trefoil factor 3 promotes metastatic seeding and predicts poor survival outcome of patients with mammary carcinoma
Introduction Recurrence or early metastasis remains the predominant cause of mortality in
patients with estrogen receptor positive (ER+) mammary carcinoma (MC). However, the …
patients with estrogen receptor positive (ER+) mammary carcinoma (MC). However, the …
Classification of breast cancer subtypes by combining gene expression and DNA methylation data
Selecting the most promising treatment strategy for breast cancer crucially depends on
determining the correct subtype. In recent years, gene expression profiling has been …
determining the correct subtype. In recent years, gene expression profiling has been …
Trefoil factor 3 promotes pancreatic carcinoma progression via WNT pathway activation mediated by enhanced WNT ligand expression
F Cheng, X Wang, YS Chiou, C He, H Guo… - Cell death & …, 2022 - nature.com
Pancreatic ductal adenocarcinoma (PDAC) is a major cause of cancer-related mortality with
a dismal prognosis that has changed little over the past few decades. Further understanding …
a dismal prognosis that has changed little over the past few decades. Further understanding …
Identification of genomic signatures in circulating tumor cells from breast cancer
Levels of circulating tumor cells (CTCs) in blood have prognostic value in early and
metastatic breast cancer. CTCs also show varying degrees of concordance with molecular …
metastatic breast cancer. CTCs also show varying degrees of concordance with molecular …
[HTML][HTML] TFF3 is a valuable predictive biomarker of endocrine response in metastatic breast cancer
FEB May, BR Westley - Endocrine-related cancer, 2015 - ncbi.nlm.nih.gov
The stratification of breast cancer patients for endocrine therapies by oestrogen or
progesterone receptor expression is effective but imperfect. The present study aims were to …
progesterone receptor expression is effective but imperfect. The present study aims were to …