Methylglyoxal–an emerging biomarker for diabetes mellitus diagnosis and its detection methods

LR Bhat, S Vedantham, UM Krishnan… - Biosensors and …, 2019 - Elsevier
Diabetes Mellitus (DM) is one among the supreme metabolic issues observed in history
since 3000 BCE and has gained much interest recently due to the increasing number of …

The potential influence of advanced glycation end products and (s) RAGE in rheumatic diseases

C Delrue, R Speeckaert, JR Delanghe… - International Journal of …, 2023 - mdpi.com
Advanced glycation end products (AGEs) are a class of compounds formed by
nonenzymatic interactions between reducing sugars and proteins, lipids, or nucleic acids …

Advanced glycation end-products (Ages) and their soluble receptor (srage) in women suffering from systemic lupus erythematosus (SLE)

A Nowak, B Przywara-Chowaniec… - Cells, 2021 - mdpi.com
Systemic lupus erythematosus (SLE) is characterized by abnormal action of the immune
system and a state of chronic inflammation. The disease can cause life-threatening …

Recent advances in the potential of Phyllanthus emblica L. and its related foods for combating metabolic diseases through methylglyoxal trapping: Phyllanthus …

SY Chen, IC Chiang, YY Chen, YH Hsu… - Food Research …, 2024 - Elsevier
Methylglyoxal (MG) serves as the primary precursor for the nonenzymatic glycation of
proteins and DNA, leading to advanced glycation end products (AGEs). Regular intake of …

Methods to investigate advanced glycation end-product and their application in clinical practice

D Corica, G Pepe, M Currò, T Aversa, A Tropeano… - Methods, 2022 - Elsevier
Advanced glycation end-products (AGEs) are heterogeneous compounds of irreversible
adducts principally derived from nonenzymatic glycation and glycoxidation of proteins. An …

Recent advances in histone glycation: emerging role in diabetes and cancer

AR Mir, S Habib, M Uddin - Glycobiology, 2021 - academic.oup.com
Ever increasing information on genome and proteome has offered fascinating details and
new opportunities to understand the molecular biology. It is now known that histone proteins …

Comprehensive insights into rheumatoid arthritis: Pathophysiology, current therapies and herbal alternatives for effective disease management

A Chatterjee, M Jayaprakasan… - Phytotherapy …, 2024 - Wiley Online Library
Rheumatoid arthritis is a chronic autoimmune inflammatory disease characterized by
immune response overexpression, causing pain and swelling in the synovial joints. This …

[HTML][HTML] Pararamosis, a Neglected Tropical Disease Induced by Premolis semirufa Caterpillar Toxins: Investigating Their Effects on Synovial Cell Inflammation

PC Pohl, IM Villas-Boas, G Pidde… - … Journal of Molecular …, 2024 - pmc.ncbi.nlm.nih.gov
Pararamosis, also known as Pararama-associated phalangeal periarthritis, is a neglected
tropical disease primarily affecting rubber tappers in the Amazon region. It is caused by …

Modulation of Alkaline Phosphatase Based ELISA in the Presence of Ions and Citrate Stabilized Nanoparticles

A Arsalan, SFF Zofair, MA Khan, SM Zakariya… - Catalysis Letters, 2024 - Springer
Alkaline phosphatase (ALP) is extensively used in various diagnostic assays including
ELISA. Diagnostic methods/biosensors having a high limit of detection are often modified by …

Thymoquinone provides structural protection of human hemoglobin against oxidative damage: Biochemical studies

Z Rasheed, A Alharbi, A Alrakebeh, K Almansour… - Biochimie, 2022 - Elsevier
Hydroxyl radicals (OH.) are one of the most active reactive oxidants recognized for their
deleterious effects to cause protein oxidative damage. Thymoquinone, a monoterpene …