DNA methylation and cardiovascular disease in humans: a systematic review and database of known CpG methylation sites
M Krolevets, V Cate, JH Prochaska, A Schulz… - Clinical …, 2023 - Springer
Background Cardiovascular disease (CVD) is the leading cause of death worldwide and
considered one of the most environmentally driven diseases. The role of DNA methylation in …
considered one of the most environmentally driven diseases. The role of DNA methylation in …
DNA methylation changes of whole blood cells in response to active smoking exposure in adults: a systematic review of DNA methylation studies
X Gao, M Jia, Y Zhang, LP Breitling, H Brenner - Clinical epigenetics, 2015 - Springer
Active smoking is a major preventable public health problem and an established critical
factor for epigenetic modification. In this systematic review, we identified 17 studies …
factor for epigenetic modification. In this systematic review, we identified 17 studies …
Epigenetic signatures of cigarette smoking
Background—DNA methylation leaves a long-term signature of smoking exposure and is
one potential mechanism by which tobacco exposure predisposes to adverse health …
one potential mechanism by which tobacco exposure predisposes to adverse health …
DNA methylation signatures in peripheral blood strongly predict all-cause mortality
Y Zhang, R Wilson, J Heiss, LP Breitling… - Nature …, 2017 - nature.com
DNA methylation (DNAm) has been revealed to play a role in various diseases. Here we
performed epigenome-wide screening and validation to identify mortality-related DNAm …
performed epigenome-wide screening and validation to identify mortality-related DNAm …
Overview of polyamines as nutrients for human healthy long life and effect of increased polyamine intake on DNA methylation
K Soda - Cells, 2022 - mdpi.com
Polyamines, spermidine and spermine, are synthesized in every living cell and are therefore
contained in foods, especially in those that are thought to contribute to health and longevity …
contained in foods, especially in those that are thought to contribute to health and longevity …
Maternal smoking during pregnancy induces persistent epigenetic changes into adolescence, independent of postnatal smoke exposure and is associated with …
Background: Several studies have shown effects of current and maternal smoking during
pregnancy on DNA methylation of CpG sites in newborns and later in life. Here, we …
pregnancy on DNA methylation of CpG sites in newborns and later in life. Here, we …
[HTML][HTML] Higher diet quality relates to decelerated epigenetic aging
Background DNA methylation–based epigenetic age measures have been used as
biological aging markers and are associated with a healthy lifespan. Few population-based …
biological aging markers and are associated with a healthy lifespan. Few population-based …
Large-scale hypothesis testing for causal mediation effects with applications in genome-wide epigenetic studies
In genome-wide epigenetic studies, it is of great scientific interest to assess whether the
effect of an exposure on a clinical outcome is mediated through DNA methylations …
effect of an exposure on a clinical outcome is mediated through DNA methylations …
DNA methylation signatures of incident coronary heart disease: findings from epigenome-wide association studies
Y Xia, A Brewer, JT Bell - Clinical Epigenetics, 2021 - Springer
Coronary heart disease (CHD) is a type of cardiovascular disease (CVD) that affects the
coronary arteries, which provide oxygenated blood to the heart. It is a major cause of …
coronary arteries, which provide oxygenated blood to the heart. It is a major cause of …
Smoking-associated DNA methylation markers predict lung cancer incidence
Y Zhang, M Elgizouli, B Schöttker, B Holleczek… - Clinical …, 2016 - Springer
Background Newly established blood DNA methylation markers that are strongly associated
with smoking might open new avenues for lung cancer (LC) screening. We aimed to assess …
with smoking might open new avenues for lung cancer (LC) screening. We aimed to assess …