Contributions of histone variants in nucleosome structure and function
H Kurumizaka, T Kujirai, Y Takizawa - Journal of molecular biology, 2021 - Elsevier
Chromatin compacts genomic DNA in eukaryotes. The primary chromatin unit is the
nucleosome core particle, composed of four pairs of the core histones, H2A, H2B, H3, and …
nucleosome core particle, composed of four pairs of the core histones, H2A, H2B, H3, and …
Chromatin dynamics during the cell cycle at centromeres
S Müller, G Almouzni - Nature Reviews Genetics, 2017 - nature.com
Centromeric chromatin undergoes major changes in composition and architecture during
each cell cycle. These changes in specialized chromatin facilitate kinetochore formation in …
each cell cycle. These changes in specialized chromatin facilitate kinetochore formation in …
Structure of the human inner kinetochore bound to a centromeric CENP-A nucleosome
Kinetochores assemble onto specialized centromeric CENP-A (centromere protein A)
nucleosomes (CENP-ANuc) to mediate attachments between chromosomes and the mitotic …
nucleosomes (CENP-ANuc) to mediate attachments between chromosomes and the mitotic …
Structure of the human inner kinetochore CCAN complex and its significance for human centromere organization
Centromeres are specialized chromosome loci that seed the kinetochore, a large protein
complex that effects chromosome segregation. A 16-subunit complex, the constitutive …
complex that effects chromosome segregation. A 16-subunit complex, the constitutive …
The CENP-LN complex forms a critical node in an integrated meshwork of interactions at the centromere-kinetochore interface
During mitosis, the macromolecular kinetochore complex assembles on the centromere to
orchestrate chromosome segregation. The properties and architecture of the 16-subunit …
orchestrate chromosome segregation. The properties and architecture of the 16-subunit …
CENP-N promotes the compaction of centromeric chromatin
The histone variant CENP-A is the epigenetic determinant for the centromere, where it is
interspersed with canonical H3 to form a specialized chromatin structure that nucleates the …
interspersed with canonical H3 to form a specialized chromatin structure that nucleates the …
Decoding the centromeric nucleosome through CENP-N
Centromere protein (CENP) A, a histone H3 variant, is a key epigenetic determinant of
chromosome domains known as centromeres. Centromeres nucleate kinetochores, multi …
chromosome domains known as centromeres. Centromeres nucleate kinetochores, multi …
Structural mechanisms of centromeric nucleosome recognition by the kinetochore protein CENP-N
Accurate chromosome segregation requires the proper assembly of kinetochore proteins. A
key step in this process is the recognition of the histone H3 variant CENP-A in the …
key step in this process is the recognition of the histone H3 variant CENP-A in the …
Structural insights into human CCAN complex assembled onto DNA
In mitosis, accurate chromosome segregation depends on kinetochores that connect
centromeric chromatin to spindle microtubules. The centromeres of budding yeast, which are …
centromeric chromatin to spindle microtubules. The centromeres of budding yeast, which are …
Dynamics of kinetochore structure and its regulations during mitotic progression
M Hara, T Fukagawa - Cellular and Molecular Life Sciences, 2020 - Springer
Faithful chromosome segregation during mitosis in eukaryotes requires attachment of the
kinetochore, a large protein complex assembled on the centromere of each chromosome, to …
kinetochore, a large protein complex assembled on the centromere of each chromosome, to …