Metabolic abnormalities lead to the dysfunction of metabolic pathways and metabolite
accumulation or deficiency which is well-recognized hallmarks of diseases. Metabolite …

Natural products and their structural analogues have historically made a major contribution
to pharmacotherapy, especially for cancer and infectious diseases. Nevertheless, natural …

In-cell structural biology aims at extracting structural information about proteins or nucleic
acids in their native, cellular environment. This emerging field holds great promise and is …

Background Whey is the largest volume co-product of the dairy industry and over the last two
centuries, a significant amount of research has been dedicated to uncover its chemical …

During the past few decades, the direct analysis of metabolic intermediates in biological
samples has greatly improved the understanding of metabolic processes. The most used …

The field of metabolomics continues to grow exponentially as it contributes significantly to
numerous disciplines, including biomedicine, pharmacology, drug development, and …

Direct diagnosis and accurate assessment of metabolic syndrome (MetS) allow for prompt
clinical interventions. However, traditional diagnostic strategies overlook the complex …

Nuclear magnetic resonance (NMR) spectroscopy is an important analytical technique in
metabolomics. Because it provides atomic-level detail of small molecules, NMR is …

To gain insight into the complex microbiome-gut-brain axis in irritable bowel syndrome (IBS),
several modalities of biological and clinical data must be combined. We aimed to identify …

Schizophrenia (SZ) detection enables effective treatment to improve the clinical outcome,
but objective and reliable SZ diagnostics are still limited. An ideal diagnosis of SZ suited for …