HER2‐positive breast cancer brain metastasis: a new and exciting landscape

AS Zimmer, AED Van Swearingen… - Cancer …, 2022 - Wiley Online Library
Abstract Background Brain metastases (BrM) incidence is 25% to 50% in women with
advanced human epidermal growth factor receptor 2 (HER2)‐positive breast cancer …

Treatment of radiation-induced cognitive decline

A Attia, BR Page, GJ Lesser, M Chan - Current treatment options in …, 2014 - Springer
Opinion statement Radiation-induced cognitive decline in cancer survivors who have
received brain radiotherapy is an insidious problem with worsening severity over time …

Brain metastasis velocity: a novel prognostic metric predictive of overall survival and freedom from whole-brain radiation therapy after distant brain failure following …

M Farris, ER McTyre, CK Cramer, R Hughes… - International Journal of …, 2017 - Elsevier
Purpose Prior statistical models attempted to identify risk factors for time to distant brain
failure (DBF) or time to salvage whole-brain radiation therapy (WBRT) to predict the benefit …

Risk factors and survival outcomes in patients with breast cancer and lung metastasis: a population‐based study

W Xiao, S Zheng, P Liu, Y Zou, X Xie, P Yu… - Cancer …, 2018 - Wiley Online Library
The risk factors for morbidity and mortality in breast cancer lung metastases (BCLM) patients
still remain poorly identified. The aim of this study was to assess the incidence and survival …

Immunotherapy is associated with improved survival and decreased neurologic death after SRS for brain metastases from lung and melanoma primaries

CM Lanier, R Hughes, T Ahmed… - Neuro-oncology …, 2019 - academic.oup.com
Background The effect of immunotherapy on brain metastasis patients remains incompletely
understood. Our goal was to evaluate its effect on survival, neurologic death, and patterns of …

Multi-omics analysis of brain metastasis outcomes following craniotomy

J Su, Q Song, S Qasem, S O'Neill, J Lee… - Frontiers in …, 2021 - frontiersin.org
Background The incidence of brain metastasis continues to increase as therapeutic
strategies have improved for a number of solid tumors. The presence of brain metastasis is …

A nomogram for predicting distant brain failure in patients treated with gamma knife stereotactic radiosurgery without whole brain radiotherapy

DN Ayala-Peacock, AM Peiffer, JT Lucas… - Neuro …, 2014 - academic.oup.com
Background We review our single institution experience to determine predictive factors for
early and delayed distant brain failure (DBF) after radiosurgery without whole brain …

Predictors of neurologic and nonneurologic death in patients with brain metastasis initially treated with upfront stereotactic radiosurgery without whole-brain radiation …

ER McTyre, AG Johnson, J Ruiz, S Isom… - Neuro …, 2017 - academic.oup.com
Background. In this study we attempted to discern the factors predictive of neurologic death
in patients with brain metastasis treated with upfront stereotactic radiosurgery (SRS) without …

Temozolomide in secondary prevention of HER2-positive breast cancer brain metastases

AS Zimmer, SM Steinberg, DD Smart, MR Gilbert… - Future …, 2020 - Taylor & Francis
Brain metastases occur in up to 25–55% of patients with metastatic HER2-positive breast
cancer. Standard treatment has high rates of recurrence or progression, limiting survival and …

Stereotactic radiotherapy for large solitary brain metastases

L Feuvret, S Vinchon, V Martin, I Lamproglou… - Cancer …, 2014 - Elsevier
Purpose To assess effectiveness and toxicity levels of stereotactic radiation therapy without
whole brain radiation therapy in patients with solitary brain metastases larger than 3 cm …