We overview recent research trends in cancer genomics, bioinformatics tools development
and medical genetics, based on results discussed in papers collections “Medical Genetics …

Oxidative phosphorylation (OxPhos) is the basic function of mitochondria, although the
landscape of mitochondrial functions is continuously growing to include more aspects of …

Background Head and neck paragangliomas (HNPs) have been associated with gene
mutations in the succinate dehydrogenase (SDH) complex, but the clinical significance …

Complex II (CII) activity controls phenomena that require crosstalk between metabolism and
signaling, including neurodegeneration, cancer metabolism, immune activation, and …

Vagal paraganglioma is a rare finding that develops from paraganglionic tissue found
around the vagus nerve; it has a prevalence of 0.012% of all tumors. It is the third most …

https://doi. org/10.1186/s12920-020-00786-x 46% of all pathogenic T> C variants, while A>
G editors may precisely target 6900 mutations (34% of all pathogenic G> A variants). Thus …

Introduction and importance Vagal paragangliomas of neck are rare tumours of neural crest
origin usually arising in elderly age with female predominance. They have a vague clinical …

Background: Vagal paraganglioma (VPGL) is a very rare neuroendocrine tumor arising from
the paraganglion associated with the vagus nerve. VPGL is mainly characterized by an …

During embryonic development, nerve-associated Schwann cell precursors (SCPs) give rise
to chromaffin cells of the adrenal gland via the “bridge” transient stage, according to recent …

Mitochondria are essential organelles for most eukaryotic cells, containing intricate networks
of numerous proteins. These include, among others, complexes I-IV of the electron transport …