The atria provide an important contribution to cardiac function. 1, 2 Besides their impact on
ventricular filling, they serve as a volume reservoir, host pacemaker cells and important parts …

The discovery that mammalian cells have the ability to synthesize the free radical nitric oxide
(NO) has stimulated an extraordinary impetus for scientific research in all the fields of …

The atria provide an important contribution to cardiac function. 1, 2 Besides their impact on
ventricular filling, they serve as a volume reservoir, host pacemaker cells and important parts …

At least 468 individual genes have been manipulated by molecular methods to study their
effects on the initiation, promotion, and progression of atherosclerosis. Most clinicians and …

Context: Diabetic complications appear to be multifactorial in origin, but in particular, the
biochemical process of advanced glycation, which is accelerated in diabetes as a result of …

Diabetes is a recognized risk factor for cardiovascular diseases and heart failure. Diabetic
cardiovascular dysfunction also underscores the development of diabetic retinopathy …

Poly (ADP-ribose) polymerase-1 (PARP-1) is a member of the PARP enzyme family
consisting of PARP-1 and several recently identified novel poly (ADP-ribosylating) enzymes …

The aim of this article is to describe the current and potential clinical translation of
pharmacological inhibitors of poly (ADP-ribose) polymerase (PARP) for the therapy of …

Diabetic complications are the major cause of morbidity and mortality in persons with
diabetes. Chronic hyperglycemia is a major initiator of diabetic microvascular complications …

Collectively, angiogenic ocular conditions represent the leading cause of irreversible vision
loss in developed countries. In the US, for example, retinopathy of prematurity, diabetic …