An enantioselective protonation strategy has been successfully applied to the synthesis of
chiral α-tertiary azaarenes. With a dual catalytic system involving a chiral phosphoric acid …

Oxadiazoles experienced an almost 80-year long period of scientific lethargy before they
tickled the curiosity of chemists. The study of chemical and photochemical reactivity of 1, 2, 4 …

Organic superbases are a distinct and increasingly utilized class of Brønsted base that
possess properties complementary to common inorganic bases. This Concept article …

Alkenes and their functionalized derivatives represent a versatile class of building blocks in
organic synthesis. The traditional synthetic methods include Wittig olefination, Peterson …

Catalytic asymmetric conjugate addition reactions represent a powerful strategy to access
chiral molecules in contemporary organic synthesis. However, their applicability to …

Alkenylpyridines are important pharmaceutical cores as well as versatile building blocks in
organic synthesis. Heck reaction represents one of the most powerful platform for the …

The first enantioselective sulfa-Michael addition of alkyl thiols to alkenyl benzimidazoles,
enabled by a bifunctional iminophosphorane (BIMP) organocatalyst, is described. The …

We describe a synergistic catalysis strategy for the asymmetric direct addition of simple
aldehydes to 4-vinylpyridines. By means of independent activation of weakly electrophilic 4 …

The radical–radical couplings of readily available alkylarenes and diarylmethanes with
cheap and abundant 4-cyanopyridine in a stoichiometric manner at room temperature have …

General methods to prepare chiral pyridine derivatives are greatly sought after due to their
significance in medicinal chemistry. Here, we report highly enantioselective catalytic …