Photoswitchable diarylethenes: from molecular structures to biological applications

Z Li, X Zeng, C Gao, J Song, F He, T He, H Guo… - Coordination Chemistry …, 2023 - Elsevier
Diarylethene (DAE) photoswitches, known for their reversible photoinduced cyclization and
cycloreversion reactions, have shown great promise in various fields such as optical data …

[HTML][HTML] Macrocyclization reactions: the importance of conformational, configurational, and template-induced preorganization

V Marti-Centelles, MD Pandey, MI Burguete… - Chemical …, 2015 - ACS Publications
Macrocyclic structures are common synthetic targets in drug discovery,(1, 2) and therefore,
interest in their study is continuously increasing in this field.(3, 4) A classic example is …

Synergistic interaction between silver nanoparticles and membrane-permeabilizing antimicrobial peptides

S Ruden, K Hilpert, M Berditsch… - Antimicrobial agents …, 2009 - Am Soc Microbiol
Silver nanoparticles, as well as antimicrobial peptides (AMPs), can be used to fight
infectious diseases. Since AMPs are known to permeabilize bacterial membranes and might …

Host Materials Transformable in Tumor Microenvironment for Homing Theranostics.

PP Yang, Q Luo, GB Qi, YJ Gao, BN Li… - … (Deerfield Beach, Fla …, 2017 - europepmc.org
A pathology-adaptive nanosystem, in which nest-like hosts are built based on nanofibers
that are transformed from iv injected nanoparticles under the acidic tumor microenvironment …

Controlling biological activity with light: diarylethene‐containing cyclic peptidomimetics

O Babii, S Afonin, M Berditsch, S Reiβer… - Angewandte …, 2014 - Wiley Online Library
Photobiological processes in nature are usually triggered by nonpeptidic chromophores or
by modified side chains. A system is presented in which the polypeptide backbone itself can …

Analysis of the mechanism of action of potent antibacterial hetero-tri-organometallic compounds: a structurally new class of antibiotics

M Wenzel, M Patra, CHR Senges, I Ott… - ACS chemical …, 2013 - ACS Publications
Two hetero-tri-organometallic compounds with potent activity against Gram-positive bacteria
including multi-resistant Staphylococcus aureus (MRSA) were identified. The compounds …

Membrane-active peptides and the clustering of anionic lipids

P Wadhwani, RF Epand, N Heidenreich, J Bürck… - Biophysical journal, 2012 - cell.com
There is some overlap in the biological activities of cell-penetrating peptides (CPPs) and
antimicrobial peptides (AMPs). We compared nine AMPs, seven CPPs, and a fusion peptide …

A comparison of linear and cyclic peptoid oligomers as potent antimicrobial agents

ML Huang, SBY Shin, MA Benson, VJ Torres… - …, 2012 - Wiley Online Library
We investigated the antimicrobial activities of N‐substituted glycine “peptoid” oligomers
incorporating cationic and hydrophobic side chains. Head‐to‐tail macrocyclization was …

Global analysis of peptide cyclization efficiency

A Thakkar, TB Trinh, D Pei - ACS combinatorial science, 2013 - ACS Publications
Cyclic peptides are of considerable interest in drug discovery and nanotechnology.
However, macrocyclization of peptides and other compounds has often been perceived as …

A cell-penetrating peptide derived from human lactoferrin with conformation-dependent uptake efficiency

F Duchardt, IR Ruttekolk, WPR Verdurmen… - Journal of Biological …, 2009 - ASBMB
The molecular events that contribute to the cellular uptake of cell-penetrating peptides (CPP)
are still a matter of intense research. Here, we report on the identification and …