The dopamine hypothesis of schizophrenia has been one of the most enduring ideas in
psychiatry. Initially, the emphasis was on a role of hyperdopaminergia in the etiology of …

This review critically summarizes the neuropathology and genetics of schizophrenia, the
relationship between them, and speculates on their functional convergence. The …

Patients with mental disorders show many biological abnormalities which distinguish them
from normal volunteers; however, few of these have led to tests with clinical utility. Several …

Improvements in understanding the neurobiological basis of mental illness have
unfortunately not translated into major advances in treatment. At this point, it is clear that …

Distraction and reappraisal are two commonly used forms of cognitive emotion regulation.
Functional neuroimaging studies have shown that each one depends upon interactions …

BACKGROUND: The large quantity of systematic reviews of magnetic resonance imaging
studies in schizophrenia challenges their meaningful interpretation. This meta-review …

The past several years have seen a resurgence of interest in understanding the
psychological and neural bases of what are often referred to as “negative symptoms” in …

BackgroundStudies of people with schizophrenia assessed using magnetic resonance
imaging (MRI) usually include patients with first-episode and chronic disease, yet brain …

Neurodevelopmental models of schizophrenia that identify longitudinal precursors of illness
have been of great heuristic importance focusing most etiologic research over the past two …

BACKGROUND: Although structural neuroimaging methods have been widely used to study
brain morphology in schizophrenia, synthesizing this literature has been difficult. With the …