Role of lipid composition in the antimicrobial peptide double cooperative effect

Y Hou, K Sugihara - Langmuir, 2023 - ACS Publications
The antimicrobial peptide double cooperative effect, where the mixture of two major
antimicrobial peptides LL-37 and HNP1 kills bacteria more efficiently while minimizing the …

[HTML][HTML] De novo designed self-assembling helicomimetic lipooligoureas with antibacterial activity

P Bachurska-Szpala, K Burdach, R Lasek… - European Journal of …, 2023 - Elsevier
The overuse of antibiotics has led to a rise in infections caused by multidrug-resistant
bacteria, resulting in a need for new antibacterial compounds with different modes of action …

Cholesterol levels affect the performance of AuNPs-decorated thermo-sensitive liposomes as nanocarriers for controlled doxorubicin delivery

MC García, N Naitlho, JM Calderón-Montaño, E Drago… - Pharmaceutics, 2021 - mdpi.com
Stimulus-responsive liposomes (L) for triggering drug release to the target site are
particularly useful in cancer therapy. This research was focused on the evaluation of the …

Design, Synthesis, and Bioactivity Investigation of Cyclic Lipopeptide Antibiotics Containing Eight to Nine Amino Acids

HX Yang, ZS Xie, H Yi, J Jin, J Geng… - Journal of Medicinal …, 2023 - ACS Publications
The current global issue of antibiotic resistance is serious, and there is an urgent
requirement of developing novel antibiotics. Octapeptins have recently regained interest …

Surface-Bioengineered Extracellular Vesicles Seeking Molecular Biotargets in Lung Cancer Cells

A Kowalczyk, D Dziubak, A Kasprzak… - … Applied Materials & …, 2024 - ACS Publications
Personalized medicine is a new approach to modern oncology. Here, to facilitate the
application of extracellular vesicles (EVs) derived from lung cancer cells as potent advanced …

[HTML][HTML] Is lipophilicity the main factor determining the effective drug penetration through lipid membranes? Combined GIXD and PM-IRRAS studies on the example of …

D Matyszewska, M Zaborowska, P Fontaine - Journal of Molecular Liquids, 2023 - Elsevier
Cell membranes constitute the first barrier for the drugs on their way to the cell. Therefore,
their penetration determines the effectivity of the treatment and is defined by the drug-lipid …

[引用][C] Mechanism of action and selectivity of linear lipopeptide battacin using model biological membranes

NMM Darbi - 2022 - University of Auckland