Novel antibacterial therapies are urgently required to tackle the increasing number of
multidrug‐resistant pathogens. Identification of new antimicrobial targets is critical to avoid …

New antimicrobial approaches are essential to counter antimicrobial resistance. The drug
development pipeline is exhausted with the emergence of resistance, resulting in …

Methicillin-resistant Staphylococcus aureus (MRSA) is the leading cause of wound
infections, often progressing into serious invasive bloodstream infections. MRSA …

A series of small-molecule fluoroquinolones were synthesized, characterized by HRMS and
NMR spectroscopy, and screened for their antibacterial activity against MRSA, P …

Aminoglycosides are vital antibiotics for treating severe Gram-negative bacterial infections,
but the evolution of resistance mechanisms creates huge treatment hurdles. This work …