Revisiting the role of neurotransmitters in epilepsy: An updated review

E Akyuz, AK Polat, E Eroglu, I Kullu, E Angelopoulou… - Life sciences, 2021 - Elsevier
Epilepsy is a neurologicaldisorder characterized by persistent predisposition to recurrent
seizurescaused by abnormal neuronal activity in the brain. Epileptic seizures maydevelop …

Zebrafish as an innovative tool for epilepsy modeling: state of the art and potential future directions

M D'Amora, A Galgani, M Marchese, F Tantussi… - International journal of …, 2023 - mdpi.com
This article discusses the potential of Zebrafish (ZF)(Danio Rerio), as a model for epilepsy
research. Epilepsy is a neurological disorder affecting both children and adults, and many …

Schaftoside suppresses pentylenetetrazol-induced seizures in zebrafish via suppressing apoptosis, modulating inflammation, and oxidative stress

J Dang, YN Paudel, X Yang, Q Ren… - ACS chemical …, 2021 - ACS Publications
The lack of disease-modifying therapeutic strategies against epileptic seizures has caused a
surge in preclinical research focused on exploring and developing novel therapeutic …

Allergic reactions to tick saliva components in zebrafish model

M Contreras, R Vaz-Rodrigues, L Mazuecos, M Villar… - Parasites & vectors, 2023 - Springer
Abstract Background Alpha-Gal syndrome (AGS) is a tick-borne food allergy caused by IgE
antibodies against the glycan galactose-alpha-1, 3-galactose (α-Gal) present in …

Role of innate immune receptor TLR4 and its endogenous ligands in epileptogenesis

YN Paudel, E Angelopoulou, E Akyuz, C Piperi… - Pharmacological …, 2020 - Elsevier
Understanding the interplay between the innate immune system, neuroinflammation, and
epilepsy might offer a novel perspective in the quest of exploring new treatment strategies …

Comparison of the chronic toxicities of graphene and graphene oxide toward adult zebrafish by using biochemical and phenomic approaches

G Audira, JS Lee, P Siregar, N Malhotra… - Environmental …, 2021 - Elsevier
Graphene (GR) and graphene oxide (GO) are widely being used as promising candidates
for biomedical applications, as well as for bio-sensing, drug delivery, and anticancer …

Naturally occurring HMGB1 inhibitor, glycyrrhizin, modulates chronic seizures-induced memory dysfunction in zebrafish model

YN Paudel, SU Khan, I Othman… - ACS Chemical …, 2021 - ACS Publications
Glycyrrhizin (GL) is a well-known pharmacological inhibitor of high mobility group box 1
(HMGB1) and is abundantly present in the licorice root (Glycyrrhiza radix). HMGB1 protein, a …

Chemically-induced epileptic seizures in zebrafish: A systematic review

R Chitolina, M Gallas-Lopes, CG Reis, R Benvenutti… - Epilepsy Research, 2023 - Elsevier
The use of zebrafish as a model organism is gaining evidence in the field of epilepsy as it
may help to understand the mechanisms underlying epileptic seizures. As zebrafish assays …

The Influence of Palmatine Isolated from Berberis sibirica Radix on Pentylenetetrazole-Induced Seizures in Zebrafish

K Gawel, W Kukula-Koch, D Nieoczym, K Stepnik… - Cells, 2020 - mdpi.com
Palmatine (PALM) and berberine (BERB) are widely identified isoquinoline alkaloids among
the representatives of the Berberidaceae botanical family. The antiseizure activity of BERB …

Revisiting the impact of neurodegenerative proteins in epilepsy: focus on alpha-synuclein, beta-amyloid, and tau

YN Paudel, E Angelopoulou, C Piperi, I Othman… - Biology, 2020 - mdpi.com
Lack of disease-modifying therapy against epileptogenesis reflects the complexity of the
disease pathogenesis as well as the high demand to explore novel treatment strategies. In …