Force spectroscopy of single cells using atomic force microscopy

A Viljoen, M Mathelié-Guinlet, A Ray… - Nature Reviews …, 2021 - nature.com
Physical forces and mechanical properties have critical roles in cellular function, physiology
and disease. Over the past decade, atomic force microscopy (AFM) techniques have …

Mechanomicrobiology: how bacteria sense and respond to forces

YF Dufrêne, A Persat - Nature Reviews Microbiology, 2020 - nature.com
Microorganisms have evolved to thrive in virtually any terrestrial and marine environment,
exposing them to various mechanical cues mainly generated by fluid flow and pressure as …

A comprehensive guide to pilus biogenesis in Gram-negative bacteria

MK Hospenthal, TRD Costa, G Waksman - Nature reviews microbiology, 2017 - nature.com
Pili are crucial virulence factors for many Gram-negative pathogens. These surface
structures provide bacteria with a link to their external environments by enabling them to …

Demonstration of catch bonds between an integrin and its ligand

F Kong, AJ García, AP Mould, MJ Humphries… - Journal of Cell …, 2009 - rupress.org
Binding of integrins to ligands provides anchorage and signals for the cell, making them
prime candidates for mechanosensing molecules. How force regulates integrin–ligand …

Antioxidant, Volatile Compounds; Antimicrobial, Anti-Inflammatory, and Dermatoprotective Properties of Cedrus atlantica (Endl.) Manetti Ex Carriere Essential Oil: In …

N El Hachlafi, HN Mrabti, SH Al-Mijalli, M Jeddi… - Molecules, 2023 - mdpi.com
Cedrus atlantica (Endl.) Manetti ex Carriere is an endemic tree possessing valuable health
benefits which has been widely used since time immemorial in international traditional …

Mechanically Activated Integrin Switch Controls α5β1 Function

JC Friedland, MH Lee, D Boettiger - Science, 2009 - science.org
The cytoskeleton, integrin-mediated adhesion, and substrate stiffness control a common set
of cell functions required for development and homeostasis that are often deranged in …

Extra-intestinal pathogenic Escherichia coli (ExPEC): disease, carriage and clones

AP Dale, N Woodford - Journal of Infection, 2015 - Elsevier
Extra-intestinal pathogenic Escherichia coli (ExPEC) have a complex phylogeny, broad
virulence factor (VF) armament and significant genomic plasticity, and are associated with a …

Catch-bond mechanism of the bacterial adhesin FimH

MM Sauer, RP Jakob, J Eras, S Baday, D Eriş… - Nature …, 2016 - nature.com
Ligand–receptor interactions that are reinforced by mechanical stress, so-called catch-
bonds, play a major role in cell–cell adhesion. They critically contribute to widespread …

Rolling cell adhesion

RP McEver, C Zhu - Annual review of cell and developmental …, 2010 - annualreviews.org
Rolling adhesion on vascular surfaces is the first step in recruiting circulating leukocytes,
hematopoietic progenitors, or platelets to specific organs or to sites of infection or injury …

Staphylococcus aureus clumping factor A is a force-sensitive molecular switch that activates bacterial adhesion

P Herman-Bausier, C Labate… - Proceedings of the …, 2018 - National Acad Sciences
Clumping factor A (ClfA), a cell-wall–anchored protein from Staphylococcus aureus, is a
virulence factor in various infections and facilitates the colonization of protein-coated …