Major depressive disorder (MDD) is a common psychiatric illness with a wide range of
symptoms such as mood decline, loss of interest, and feelings of guilt and worthlessness …

Background The habenula is an epithalamic brain structure that acts as a neuroanatomical
hub connecting the limbic forebrain to the major monoamine centres. Abnormal habenula …

Deep brain stimulation (DBS) has shown therapeutic benefits for treatment resistant
depression (TRD). Stimulation of the subcallosal cingulate gyrus (SCG) aims to alter …

Background Previous neuroimaging has paid little attention to the differences in brain
network integration between patients with treatment-resistant depression (TRD) and non …

Identifying individuals with early mild cognitive impairment (EMCI) can be an effective
strategy for early diagnosis and delay the progression of Alzheimer's disease (AD). Many …

Background Depression is a widespread mental health disorder with complex
neurobiological underpinnings. The habenula, known as the 'anti-reward center', is thought …

Objective Previous studies have revealed abnormal degree centrality (DC) in the structural
and functional networks in the brains of patients with major depressive disorder (MDD) …

Background A significant proportion of patients with major depressive disorder are resistant
to antidepressant medication and psychological treatments. A core symptom of treatment …

Background Previous studies found that transcutaneous auricular vagus nerve stimulation
(taVNS) was clinically effective in treating a case of treatment-resistant depression (TRD) …

Background The aim of this study was to investigate the functional abnormalities between
the nucleus accumbens (NAc) and the whole brain in individuals with Insomnia Disorder (ID) …