Recent developments in 1, 6-addition reactions of para-quinone methides (p-QMs)

JY Wang, WJ Hao, SJ Tu, B Jiang - Organic Chemistry Frontiers, 2020 - pubs.rsc.org
In recent years, para-quinone methides (p-QMs) have emerged as attractive and versatile
synthons in organic synthesis owing to their high reactivity. Consequently, p-QM chemistry …

Bifunctional amine‐squaramides: powerful hydrogen‐bonding organocatalysts for asymmetric domino/cascade reactions

P Chauhan, S Mahajan, U Kaya… - … Synthesis & Catalysis, 2015 - Wiley Online Library
Organocatalytic domino/cascade reactions provide a convenient method for the construction
of complex molecular structures bearing multiple stereocenters in a highly stereoselective …

Cooperative NHC and photoredox catalysis for the synthesis of β‐trifluoromethylated alkyl aryl ketones

QY Meng, N Döben, A Studer - … Chemie International Edition, 2020 - Wiley Online Library
Despite the great potential of radical chemistry in organic synthesis, N‐heterocyclic carbene
(NHC)‐catalyzed reactions involving radical intermediates are not well explored. This …

Combined photoredox and carbene catalysis for the synthesis of ketones from carboxylic acids

AV Bay, KP Fitzpatrick, RC Betori… - Angewandte …, 2020 - Wiley Online Library
As a key element in the construction of complex organic scaffolds, the formation of C− C
bonds remains a challenge in the field of synthetic organic chemistry. Recent advancements …

N‐Heterocyclic Carbene Catalysis via Azolium Dienolates: An Efficient Strategy for Remote Enantioselective Functionalizations

XY Chen, Q Liu, P Chauhan… - Angewandte Chemie …, 2018 - Wiley Online Library
N‐heterocyclic carbene (NHC) catalysis has emerged as a powerful strategy in organic
synthesis. In recent years a number of reviews have been published on NHC‐catalyzed …

Recent Advances in Catalytic Asymmetric Synthesis of Tertiary Alcohols via Nucleophilic Addition to Ketones

YL Liu, XT Lin - Advanced Synthesis & Catalysis, 2019 - Wiley Online Library
Chiral tertiary alcohols are an important class of organic compounds which have found wide
applications in both academia and industry. Therefore, various synthetic strategies towards …

Atroposelective Access to 1, 3‐Oxazepine‐Containing Bridged Biaryls via Carbene‐Catalyzed Desymmetrization of Imines

X Yang, L Wei, Y Wu, L Zhou, X Zhang… - Angewandte Chemie …, 2023 - Wiley Online Library
We disclose herein an atroposelective synthesis of novel bridged biaryls containing medium‐
sized rings via N‐heterocyclic carbene organocatalysis. The reaction starts with addition of …

Kinetic Resolution of 1, 1′‐Biaryl‐2, 2′‐Diols and Amino Alcohols through NHC‐Catalyzed Atroposelective Acylation

S Lu, SB Poh, Y Zhao - Angewandte Chemie International …, 2014 - Wiley Online Library
We present here a highly efficient NHC‐catalyzed kinetic resolution of a wide range of 1, 1′‐
biaryl‐2, 2′‐diols and amino alcohols to provide them in uniformly≥ 99% ee. This …

Asymmetric Synthesis of Spirobenzazepinones with Atroposelectivity and Spiro‐1, 2‐Diazepinones by NHC‐Catalyzed [3+ 4] Annulation Reactions

L Wang, S Li, M Blümel, AR Philipps… - Angewandte …, 2016 - Wiley Online Library
A strategy for the NHC‐catalyzed asymmetric synthesis of spirobenzazepinones, spiro‐1, 2‐
diazepinones, and spiro‐1, 2‐oxazepinones has been developed via [3+ 4]‐cycloaddition …

N‐Heterocyclic carbene catalyzed photoenolization/diels–alder reaction of acid fluorides

A Mavroskoufis, K Rajes, P Golz… - Angewandte Chemie …, 2020 - Wiley Online Library
The combination of light activation and N‐heterocyclic carbene (NHC) organocatalysis has
enabled the use of acid fluorides as substrates in a UVA‐light‐mediated photochemical …