The toxicology of aflatoxins as a basis for public health decisions

CP Wild, PC Turner - Mutagenesis, 2002 - academic.oup.com
Aflatoxins have been extensively studied with respect to their mechanisms of toxicity. An
understanding of metabolism, DNA adduct induction, mutagenicity and carcinogenicity has …

[HTML][HTML] DNA damage by mycotoxins

JS Wang, JD Groopman - Mutation Research/Fundamental and Molecular …, 1999 - Elsevier
Mycotoxins are toxic fungal metabolites which are structurally diverse, common
contaminants of the ingredients of animal feed and human food. To date, mycotoxins with …

The chemistry and biology of aflatoxin B1: from mutational spectrometry to carcinogenesis

ME Smela, SS Currier, EA Bailey… - …, 2001 - academic.oup.com
Dietary exposure to aflatoxin B1 (AFB1) is associated with an increased incidence of
hepatocellular carcinoma (HCC), especially in populations in which exposure to hepatitis B …

Molecular mechanisms of apoptosis induced by cytotoxic chemicals

JD Robertson, S Orrenius - Critical reviews in toxicology, 2000 - Taylor & Francis
The purpose of this review article is to discuss established molecular mechanisms of
apoptosis and their relevance to cell death induced by environmental toxicants. Apoptosis is …

Natural product DNA major groove binders

PL Hamilton, DP Arya - Natural product reports, 2012 - pubs.rsc.org
Covering: 1980 to 2011 Major groove recognition of DNA by proteins utilizes the variation in
hydrogen bond donor/acceptor content that makes DNA base-pairs distinguishable from one …

The effect on oxidative stress of aflatoxin and protective effect of lycopene on aflatoxin damage

S Yilmaz, E Kaya, MA Kisacam - Aflatoxin-control, analysis …, 2017 - books.google.com
Aflatoxin (AF) is polysubstituted bifuranocoumarins that are secondary fungal metabolites
produced by parasiticus/flavus group of the genus Aspergillus. AF is hepatotoxic …

Small molecule intercalation with double stranded DNA: implications for normal gene regulation and for predicting the biological efficacy and genotoxicity of drugs and …

LB Hendry, VB Mahesh, ED Bransome Jr… - … Molecular Mechanisms of …, 2007 - Elsevier
The binding of small molecules to double stranded DNA including intercalation between
base pairs has been a topic of research for over 40 years. For the most part, however …

[图书][B] Microbial food contamination

S Droby - 2000 - taylorfrancis.com
Microbial Food Contamination presents a more comprehensive and international view on
the subject of microbial food contamination than any book previously written. Drawing from …

The p53 codon 249 mutational hotspot in hepatocellular carcinoma is not related to selective formation or persistence of aflatoxin B1 adducts

MF Denissenko, TB Koudriakova, L Smith… - Oncogene, 1998 - nature.com
Sequence-dependent formation and lack of repair of polycyclic aromatic hydrocarbon-
induced DNA adducts correlates well with the positions of p53 mutational hotspots in …

Aflatoxins: their toxic effect on poultry and recent advances in their treatment

YA Ditta, S Mahad, U Bacha - Mycotoxins-Impact and …, 2018 - books.google.com
About 25% of total agriculture products are contaminated with aflatoxins (AFs) and other
mycotoxins in the world especially in Africa, Asia and Latin America, completely losing about …