Advances in predicting acute GVHD

AC Harris, JLM Ferrara… - British journal of …, 2013 - Wiley Online Library
Acute graft‐versus‐host disease (GVHD) is a leading cause of non‐relapse mortality
following allogeneic haematopoietic cell transplantation. Attempts to improve treatment …

Non-HLA immunogenetics in hematopoietic stem cell transplantation

AM Dickinson, D Charron - Current opinion in immunology, 2005 - Elsevier
Hematopoietic stem cell transplantation (HSCT) provides a unique environment in which to
evaluate the role of immunogenetics of both the donor and the recipient to success of the …

High-resolution HLA matching in hematopoietic stem cell transplantation: a retrospective collaborative analysis

D Fürst, C Müller, V Vucinic, D Bunjes… - Blood, The Journal …, 2013 - ashpublications.org
To validate current donor selection strategies based on previous international studies, we
retrospectively analyzed 2646 transplantations performed for hematologic malignancies in …

[HTML][HTML] National Institutes of Health consensus development project on criteria for clinical trials in chronic graft-versus-host disease: III. The 2014 Biomarker Working …

S Paczesny, FT Hakim, J Pidala, KR Cooke… - Biology of blood and …, 2015 - Elsevier
Biology-based markers to confirm or aid in the diagnosis or prognosis of chronic graft-versus-
host disease (GVHD) after allogeneic hematopoietic cell transplantation or monitor its …

Interleukins-1,-4,-6,-10, tumor necrosis factor, transforming growth factor-β, FAS, and mannose-binding protein C gene polymorphisms in Australian women: risk of …

MF Annells, PH Hart, CG Mullighan, SL Heatley… - American journal of …, 2004 - Elsevier
OBJECTIVE: The purpose of this study was to examine the relationship between preterm
birth and 22 single nucleotide polymorphisms in genes that encode cytokines and mediators …

Evaluation of published single nucleotide polymorphisms associated with acute GVHD

JW Chien, XC Zhang, W Fan, H Wang… - Blood, The Journal …, 2012 - ashpublications.org
Candidate genetic associations with acute GVHD (aGVHD) were evaluated with the use of
genotyped and imputed single-nucleotide polymorphism data from genome-wide scans of …

[HTML][HTML] Interleukin-6 in allogeneic stem cell transplantation: its possible importance for immunoregulation and as a therapeutic target

THA Tvedt, E Ersvaer, AA Tveita… - Frontiers in …, 2017 - frontiersin.org
Allogeneic stem cell transplantation is associated with a high risk of treatment-related
mortality mainly caused by infections and graft-versus-host disease (GVHD). GVHD is …

[HTML][HTML] Protective role of interleukin-10 promoter gene polymorphism in the pathogenesis of invasive pulmonary aspergillosis after allogeneic stem cell …

KW Seo, DH Kim, SK Sohn, NY Lee… - Bone Marrow …, 2005 - nature.com
The current study attempted to evaluate the association between the IL-10 promoter gene
single nucleotide polymorphism (SNP) and invasive pulmonary aspergillosis (IPA) after …

Biologic markers of chronic GVHD

J Pidala, M Sarwal, S Roedder, SJ Lee - Bone marrow transplantation, 2014 - nature.com
Biologic markers of chronic GVHD may provide insight into the pathogenesis of the
syndrome, identify molecular targets for novel interventions, and facilitate advances in …

Genetic susceptibility to fungal infections in humans

MS Lionakis - Current fungal infection reports, 2012 - Springer
Most fungal infections in humans occur in the setting of iatrogenic immunosuppression or
HIV infection. In the absence of these factors, fungi cause mild, self-limited infections that …