Because of their large surface area and immunological competence, mucosal tissues are
attractive administration and target sites for vaccination. An important characteristic of …

Chlamydia trachomatis is the leading cause of bacterial sexually transmitted disease
worldwide resulting in 4–5 million new cases of Chlamydia annually and an estimated 100 …

Abstract The interleukin-17 (IL-17) family cytokines, such as IL-17A and IL-17F, play
important protective roles in host immune response to a variety of infections such as …

Chlamydia trachomatis is the most prevalent bacterial sexually transmitted infection globally.
Antibiotic treatment is highly effective, but infection is often asymptomatic resulting in most …

Introduction Chlamydia trachomatis is the most common sexually transmitted bacterial
pathogen in the world. A licensed vaccine is not yet available, but the first vaccines have …

The optimal protective immunity against Chlamydia trachomatis (Ct) is still not fully resolved.
One of the unresolved issues concerns the importance of resident immunity, since a recent …

Background The natural course of sexually transmitted infections caused by Chlamydia
trachomatis varies between individuals. In addition to parasite and host effects, the vaginal …

Defining the mechanisms of immunity conferred by the combination of antibody and CD4+ T
cells is fundamental to designing an efficacious chlamydial vaccine. Using the Chlamydia …

Sexually transmitted Chlamydia trachomatis causes infertility, and because almost 90% of
infections are asymptomatic, a vaccine is required for its eradication. Mathematical modeling …

The uterus is a unique mucosal site where immune responses are balanced to be
permissive of a fetus, yet protective against infections. Regulation of natural killer (NK) cell …