MicroRNAs (miRNAs) are essential post-transcriptional gene regulators involved in various
neuronal and non-neuronal cell functions and play a key role in pathological conditions …

Abstract HUIBREGTSE, ME, Bazarian, JJ, Shultz, SR, and Kawata K. The biological
significance and clinical utility of emerging blood biomarkers for traumatic brain injury …

Amyotrophic lateral sclerosis (ALS) is a relentless neurodegenerative disease of the human
motor neuron system, where variability in progression rate limits clinical trial efficacy …

Amyotrophic lateral sclerosis (ALS), the major adult-onset motor neuron disease, has been
viewed almost exclusively as a disease of upper and lower motor neurons, with muscle …

Background and objectives We examined miRNA biomarkers for ALS extracted from
extracellular vesicles in blood samples using a large and diverse patient and control …

Alzheimer's disease (AD), Parkinson's disease (PD), and Amyotrophic Lateral Sclerosis
(ALS) are representative neurodegenerative diseases (NDs) characterized by degeneration …

Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disorder characterized by the
selective degeneration of upper and lower motor neurons and by the progressive weakness …

RNA metabolism is central to cellular physiopathology. Almost all the molecular pathways
underpinning biological processes are affected by the events governing the RNA life cycle …

The aim of the present study was to investigate the expression levels of microRNA (miR)‑
4722‑5p and miR‑615‑3p in Alzheimer's disease (AD) and their diagnostic value. Blood …

Parallel and massive sequencing of total RNA samples derived from different samples are
possible thanks to the use of NGS (Next Generation Sequencing) technologies. This allowed …