Epigenetic regulation in chromium-, nickel-and cadmium-induced carcinogenesis

L Zhao, R Islam, Y Wang, X Zhang, LZ Liu - Cancers, 2022 - mdpi.com
Simple Summary Environmental and occupational exposure to heavy metals are risk factors
for cancers. However, the molecular mechanisms of how heavy metals induce …

DNA damage-inducing endogenous and exogenous factors and research progress

N Liu, J Du, J Ge, SB Liu - Nucleosides, Nucleotides & Nucleic …, 2024 - Taylor & Francis
The substances that cause abnormal DNA structures are known as DNA damage-inducing
factors, and their resulting DNA damage has been extensively studied and proven to be …

[HTML][HTML] Identifying microRNAs that drive BaP-induced pulmonary effects: Multiple patterns of mechanisms underlying activation of the toxicity pathways

Y Jin, Q Zhang, Y Liu, H Guan, Y Shou, C Du… - Environment …, 2022 - Elsevier
MiRNAs are widely acknowledged as regulating gene expression and thus, being involved
in broad biological functions, environmental responses, and the process of diseases …

Hexavalent Chromium Induces Neurotoxicity by Triggering Mitochondrial Dysfunction and ROS-Mediated Signals

T Zhang, L Feng, J Cui, W Tong, H Zhao, T Wu… - Neurochemical …, 2024 - Springer
Abstract Hexavalent chromium (Cr (VI)), one of the most detrimental pollutants, has been
ubiquitously present in the environment and causes serious toxicity to humans, such as …

Potential mechanisms of lung injury and repair after hexavalent chromium [Cr (VI)] aerosol whole-body dynamic exposure

C Long, Z Su, G Hu, Q Zhang, Y Zhang, T Chen… - Chemosphere, 2024 - Elsevier
Abstract Hexavalent chromium [Cr (VI)], known as" Top Hazardous Substances", poses a
significant threat to the respiratory system. Nevertheless, the potential mechanisms of toxicity …

Platycodon grandiflorus Polysaccharides Alleviate Cr(VI)-Induced Apoptosis in DF-1 Cells via ROS-Drp1 Signal Pathway

Z Zhang, P Zheng, C Qi, Y Cui, Y Qi, K Xue, G Yan… - Life, 2022 - mdpi.com
Hexavalent chromium (Cr (VI)) is a widespread heavy metal that has been identified as a
human carcinogen, and acute or chronic exposure to Cr (VI) can cause organ damage …

Novel biomass carbon dots/chitosan hydrogel-modified TiO2: An effective reduction of Cr (VI) in various wastewater under sunlight

R Ma, J Zhu, Z Xu, Q Shi, L Zhang, J Fan - Separation and Purification …, 2025 - Elsevier
Abstract Hexavalent chromium (Cr (VI)) poses a serious threat to the environment and
human health owing to its inherent toxicity. Photocatalysis technology has garnered …

Hexavalent chromium [Cr (VI)]-induced ribosomal DNA copy number variation and DNA damage responses and their associations with nucleolar protein HRAS in …

H Xu, L Shi, L Feng, F Wu, J Chen, Y Qin, X Dong… - Environmental …, 2023 - Elsevier
The carcinogenicity of hexavalent chromium [Cr (VI)] and its compounds has been widely
recognized, yet the mechanism of genetic damage is still not fully understood. The ribosomal …

[HTML][HTML] Integrative analyses of circulating microRNA expression profile in hexavalent chromium exposed workers-a cross-sectional study within the SafeChrom …

Z Jiang, M Pan, Y Liu, T Lundh, D Pineda… - Journal of Hazardous …, 2025 - Elsevier
Background Exposure to hexavalent chromium (Cr (VI)) can occur during occupational
activities and leading lung cancer. MicroRNA (miRNA) plays an important part in …

Effects of the SEMA4B gene on hexavalent chromium [Cr (VI)]-induced malignant transformation of human bronchial epithelial cells

Y Qin, H Xu, Y Xi, L Feng, J Chen, B Xu… - Toxicology …, 2024 - academic.oup.com
Our previous study identified the potential of SEMA4B methylation level as a biomarker for
hexavalent chromium [Cr (VI)] exposure. This study aimed to investigate the role of the …