Alzheimer's disease is one of the most common dementia among elderly worldwide. There
is no therapeutic drugs until now to treat effectively this disease. One main reason is due to …

This review describes the use of Electron Paramagnetic Resonance (EPR) to measure
residue specific dynamics in proteins with a specific focus on Cu (II)‐based spin labels. First …

Oligomers formed by the amyloid β-peptide (Aβ) are pathogens in Alzheimer's disease.
Increased knowledge on the oligomerization process is crucial for understanding the …

The presence of partially structured helices in natively unfolded amyloid-β42 (Aβ42) and α-
synuclein (αS) has been shown to accelerate fibrillation in the onset of Alzheimer's and …

The development of simple and accurate methods to predict mutations in proteins remains
an unsolved challenge in modern biochemistry. It is discovered that critical information about …

Molecular dynamics simulation were performed to study the influence factors on the heat
transfer of polydimethylsiloxane (PDMS), a kind of thermal interface materials (TIMs). The …

Familial Alzheimer's disease (FAD) is passed down in family, which account for 2–3% of
about 40 million AD cases worldwide. The Flemish (A21G) mutant of amyloid β (Aβ) exhibits …

Although the N‐terminal region of Amyloid β (Aβ) peptides plays dual roles as metal‐
coordinating sites and conformational modulator, few studies have been performed to …

Recent studies uncovered a novel protective prion protein variant: V127 variant, which was
reported intrinsically resistant to prion conversion and propagation. However, the structural …

Alzheimer's disease is the most common neurodegenerative disease. Experiments and
computer simulations can complement one another to provide a full and in‐depth …