Peripheral cardiac sympathetic hyperactivity in cardiovascular disease: role of neuropeptides
High levels of sympathetic drive in several cardiovascular diseases including
postmyocardial infarction, chronic congestive heart failure and hypertension are reinforced …
postmyocardial infarction, chronic congestive heart failure and hypertension are reinforced …
Fluorescent dopamine tracer resolves individual dopaminergic synapses and their activity in the brain
PC Rodriguez, DB Pereira… - Proceedings of the …, 2013 - National Acad Sciences
We recently introduced fluorescent false neurotransmitters (FFNs) as optical tracers that
enable the visualization of neurotransmitter release at individual presynaptic terminals …
enable the visualization of neurotransmitter release at individual presynaptic terminals …
Distinct modes of dopamine and GABA release in a dual transmitter neuron
M Borisovska, ASL Bensen, G Chong… - Journal of …, 2013 - Soc Neuroscience
We now know of a surprising number of cases where single neurons contain multiple
neurotransmitters. Neurons that contain a fast-acting neurotransmitter, such as glutamate or …
neurotransmitters. Neurons that contain a fast-acting neurotransmitter, such as glutamate or …
APP+, a fluorescent analogue of the neurotoxin MPP+, is a marker of catecholamine neurons in brain tissue, but not a fluorescent false neurotransmitter
RJ Karpowicz Jr, M Dunn, D Sulzer… - ACS chemical …, 2013 - ACS Publications
We have previously introduced fluorescent false neurotransmitters (FFNs) as optical
reporters that enable visualization of individual dopaminergic presynaptic terminals and …
reporters that enable visualization of individual dopaminergic presynaptic terminals and …
Extracellular α‐synuclein enters dopaminergic cells by modulating flotillin‐1–assisted dopamine transporter endocytosis
J Kobayashi, T Hasegawa, N Sugeno… - The FASEB …, 2019 - Wiley Online Library
The neuropathological hallmarks of Parkinson's disease (PD) include the appearance of α‐
synuclein (α‐SYN)‐positive Lewy bodies (LBs) and the loss of catecholaminergic neurons …
synuclein (α‐SYN)‐positive Lewy bodies (LBs) and the loss of catecholaminergic neurons …
Ganglion-specific impairment of the norepinephrine transporter in the hypertensive rat
Hypertension is associated with enhanced cardiac sympathetic transmission, although the
exact mechanisms underlying this are still unknown. We hypothesized that defective function …
exact mechanisms underlying this are still unknown. We hypothesized that defective function …
Angiotensin AT1 – α2C-Adrenoceptor Interaction Disturbs α2A-auto-Inhibition of Catecholamine Release in Hypertensive Rats
T Berg - Frontiers in Neurology, 2013 - frontiersin.org
α2-Adrenoceptors lower central sympathetic output and peripheral catecholamine release,
and thus may prevent sympathetic hyperactivity and hypertension. α2AR also influence …
and thus may prevent sympathetic hyperactivity and hypertension. α2AR also influence …
[HTML][HTML] Dynamic monitoring of single-terminal norepinephrine transporter rate in the rodent cardiovascular system: a novel fluorescence imaging method
Here, we validate the use of a novel fluorescent norepinephrine transporter (NET) substrate
for dynamic measurements of transporter function in rodent cardiovascular tissue; this …
for dynamic measurements of transporter function in rodent cardiovascular tissue; this …
Mechanisms involved in nicotinic acetylcholine receptor-induced neurotransmitter release from sympathetic nerve terminals in the mouse vas deferens
Prejunctional nicotinic acetylcholine receptors (nAChRs) amplify postganglionic sympathetic
neurotransmission, and there are indications that intraterminal Ca2+ stores might be …
neurotransmission, and there are indications that intraterminal Ca2+ stores might be …
Resting cardiac sympathetic firing frequencies suppress terminal norepinephrine transporter uptake
The prejunctional norepinephrine transporter (NET) is responsible for the clearance of
released norepinephrine (NE) back into the sympathetic nerve terminal. NET regulation …
released norepinephrine (NE) back into the sympathetic nerve terminal. NET regulation …